View Current Travel Advisories

Trailways Bus Tickets
from Denver, CO to Clarksdale, MS

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Clarksdale, MS

Clarksdale (Greyhound Station)

Bus Station, use arrow keys or tab to explore more about this bus station

Clarksdale, MS 38614

Bus Station
Address
1604 N State St 
Clarksdale, MS 38614
Phone Number
(800) 231-2222
More Detailsabout Clarksdale (Greyhound Station) Bus Station

City InformationforDenver, CO

Get ready to hop on a bus to Denver, CO, where adventure and urban charm meet against the backdrop of the majestic Rocky Mountains. Known for its mile-high altitude and vibrant culture, the city invites explorers of all kinds to dive into its unique offerings. Begin your journey downtown with a visit to the historic Union Station, a bustling hub of shops and eateries with a distinctly local vibe. If art's your thing, the Denver Art Museum showcases everything from indigenous art to contemporary works.

For fans of the great outdoors, Denver’s proximity to nature makes it a gateway to hiking, biking, and panoramic views that will jazz up any itinerary. And speaking of jazz, don't miss out on catching a live performance at one of the city’s storied music venues.

After working up an appetite, savor some local brews in the RiNo district's craft breweries, perfect for unwinding and soaking in the friendly atmosphere. So grab your ticket for a bus to Denver, CO—your next adventure awaits in this lively, spirited city.

Scenic photo of Denver, COScenic photo of Denver, COScenic photo of Denver, CO
Scenic photo of Denver, CO
Scenic photo of Denver, CO
Scenic photo of Denver, CO

City InformationforClarksdale, MS

Get ready for a journey to Clarksdale, MS, a town overflowing with soulful blues and cultural heartbeats. Known as the “Home of the Blues,” Clarksdale welcomes you with music echoing from street corners to iconic juke joints like Ground Zero Blues Club and Red’s Lounge, where the rhythm gets into your bones. But the city's pulse doesn’t stop here—it flows through the Delta Blues Museum, narrating stories of legends like Muddy Waters.

When you're not tapping your feet to a soulful tune, immerse yourself in local art at Quapaw Canoe Company or explore quirky finds at eclectic shops downtown. Stroll down the historic blues trail, which doubles as a journey through time and music. Wrap up your visit with authentic Southern cuisine that’ll make you think you’ve found the ultimate comfort food haven.

Let the town’s Blues tradition be your soundtrack. Book your bus to Clarksdale now and dive into a vibrant world where music and hospitality create an unforgettable experience!