View Current Travel Advisories

Trailways Bus Tickets
from Buffalo, NY to San Luis Obispo, CA

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Buffalo, NY to San Luis Obispo, CA

Buses from Buffalo, NY to San Luis Obispo, CA travel the 2281mi (3670.90km) journey, taking approximately 3d, 16h, 21m. Usually, there are 3 buses operating per day. While the average ticket price for this journey is around $568.94, you can find the cheapest bus tickets for as low as $390.76.

  • Distance
    2281mi (3670.90km)
  • Average trip duration
  • Average bus ticket price
    $568.94
  • Trips per day
    3
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for San Luis Obispo, CA

San Luis Obispo (Railroad Museum)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Luis Obispo, CA 93401

Curbside Stop
Address
1940 Santa Barbara Ave 
San Luis Obispo, CA 93401
Phone Number
(800) 858-8555
More Detailsabout San Luis Obispo (Railroad Museum) Curbside Stop

City InformationforBuffalo, NY

Look out, Buffalo, NY: your bus to Buffalo is about to deliver you to a city full of surprises. Nestled by the iconic Niagara Falls, this lively town packs a punch with a mix of culture, dining, and that special Buffalo vibe. It's a haven for art enthusiasts – make sure to check out the Albright-Knox Art Gallery with its mighty collection of modern masterpieces. For architecture buffs, Frank Lloyd Wright’s Darwin D. Martin House is a must-see.

Feeling peckish? Buffalo’s got you covered with its legendary wings. A stop at a local staple like Anchor Bar or Duff’s is practically a rite of passage. Beer aficionados will appreciate the craft breweries that have popped up all throughout the town – perfect for those looking to sample local flavors.

Nature lovers, don't miss a stroll through the tranquil Buffalo and Erie County Botanical Gardens. Whether you’re hitting the town solo or with friends, Buffalo’s rich history and welcoming energy promise plenty to keep you exploring. Get on that bus to Buffalo, NY, and discover a gem of a destination where every corner has a story to tell!

Scenic photo of Buffalo, NYScenic photo of Buffalo, NYScenic photo of Buffalo, NY
Scenic photo of Buffalo, NY
Scenic photo of Buffalo, NY
Scenic photo of Buffalo, NY

City InformationforSan Luis Obispo, CA

Welcome to the charm of San Luis Obispo, CA, where your next adventure awaits. Nestled along California’s stunning Central Coast, this town is known for its unbeatable blend of relaxation and energy. Start your day on a high note as you hike up Bishop Peak, offering dazzling panoramic views that are worth every climb. Or, engage in local culture at Bubblegum Alley, the quirky landmark that sticks with you – literally!

Foodies will love the farm-to-table flavors at the region’s thriving restaurants, while those in the mood for exploration can wander around the unique shops and galleries in the historic downtown area. Feel the warmth of the community as you stroll through the picturesque streets, where friendly smiles are as common as the sunny skies.

Ready to make the journey? Your bus to San Luis Obispo promises not just a destination, but a pathway to delightful discoveries and cherished memories. So, grab that ticket, hop on board, and let San Luis Obispo captivate you with its laid-back yet lively allure!

Frequently Asked Questions about the Bus Ride

Experience a smooth bus ride from Buffalo to San Luis Obispo. With 3 buses departing to San Luis Obispo daily, our trips average 3 days 16 hours 21 minutes and start as low as $390.76. Find your bus ticket to San Luis Obispo now.