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Trailways Bus Tickets
from Sioux Falls, SD to La Crosse, WI

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Overview

About buses from Sioux Falls, SD to La Crosse, WI

Buses from Sioux Falls, SD to La Crosse, WI travel the 277mi (445.79km) journey, taking approximately 18h, 30m. Usually, there are 2 buses operating per day.

  • Distance
    277mi (445.79km)
  • Average trip duration
  • Average bus ticket price
    $0
  • Trips per day
    2
  • Top Carriers
    Jefferson Lines

Bus Station Information for La Crosse, WI

La Crosse (Grand River Station)

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La Crosse, WI 54601

Bus Station
Address
314 Jay Street 
La Crosse, WI 54601
Phone Number
(612) 849-2658/(800) 858-8555
More Detailsabout La Crosse (Grand River Station) Bus Station

La Crosse (University of Wisconsin)

Curbside Stop, use arrow keys or tab to explore more about this bus station

La Crosse, WI 54601

Curbside Stop
Address
521 East Avenue North 
La Crosse, WI 54601
Phone Number
(858) 800-8898/(800) 858-8555
More Detailsabout La Crosse (University of Wisconsin) Curbside Stop

La Crosse (Amtrak Train Station)

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La Crosse, WI 54601

Bus Station
Address
601 St. Andrew St. 
La Crosse, WI 54601
Phone Number
(858) 800-8898
More Detailsabout La Crosse (Amtrak Train Station) Bus Station

City InformationforSioux Falls, SD

Sioux Falls, SD might not be on your radar yet, but once you hop on a bus to Sioux Falls, you'll find a destination with charm to spare. This friendly town is home to stunning natural beauty, buzzing cultural scenes, and enough unique local flavor to keep any traveler entertained. Nature lovers will find themselves drawn to Falls Park, where the picturesque Big Sioux River cascades down glittering tiered rocks, a perfect spot for strolling or snapping a few Instagram-worthy pics. If you're in the mood for art, the SculptureWalk brings Sioux Falls' downtown streets alive with dozens of dynamic sculptures.

What really seals the deal? The city’s bustling downtown offers an array of unique dining experiences and cozy coffee spots where you can unwind like a local. Plus, with street festivals, local music, and that welcoming Midwestern warmth, you're set for a memorable visit. So, when the urge to explore strikes, just grab your bus tickets to Sioux Falls, and let the adventure begin!

City InformationforLa Crosse, WI

Set your sights on La Crosse, WI, where scenic beauty and vibrant culture welcome every traveler. Nestled along the Mississippi River, this charming town offers a refreshing blend of outdoor adventures and unique local experiences.

Whether you’re wandering through Riverside Park, gazing at the mighty river, or hiking the picturesque bluffs, La Crosse’s natural allure will instantly captivate you. History buffs should explore the Hixon House, a Victorian mansion rich with stories, while art enthusiasts can browse the Pump House Regional Arts Center, showcasing exciting exhibits.

Foodies, get ready to delight your taste buds. Dive into the local dining scene, where farm-to-table eateries and craft breweries offer savory bites and refreshing beers that reflect the town’s creative spirit. And if you’re in town during Oktoberfest, join in the festive fun with live music and Bavarian traditions.

Ready for a memorable getaway? Grab your tickets for a bus to La Crosse, and discover the delightful mix of charm and character waiting for you in this Wisconsin gem!

Frequently Asked Questions about the Bus Ride