View Current Travel Advisories

Trailways Bus Tickets
from San Francisco, CA to Islamorada, FL

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from San Francisco, CA to Islamorada, FL

Buses from San Francisco, CA to Islamorada, FL travel the 2596mi (4177.85km) journey, taking approximately 3d, 11h, 25m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $690.06, you can find the cheapest bus tickets for as low as $690.06.

  • Distance
    2596mi (4177.85km)
  • Average trip duration
  • Average bus ticket price
    $690.06
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for Islamorada, FL

Islamorada (Northbound - Burger King)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Islamorada, FL 33036

24 Hours
Curbside Stop
Address
82201 Overseas Hwy. 
Islamorada, FL 33036
Phone Number
(800) 858-8555
More Detailsabout Islamorada (Northbound - Burger King) Curbside Stop

Islamorada (Southbound - Trading Post)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Islamorada, FL 33036

24 Hours
Curbside Stop
Address
81868 Overseas Highway 
Islamorada, FL 33036
Phone Number
(800) 858-8555
More Detailsabout Islamorada (Southbound - Trading Post) Curbside Stop

City InformationforSan Francisco, CA

When the fog rolls into San Francisco, CA, it's like a cozy invitation to savor a town bursting with iconic charm. Take your next adventure on a bus to San Francisco, and you'll find more delights than just the Golden Gate Bridge. Begin at Fisherman’s Wharf, where street performers add a whimsical touch, and sample world-class seafood. History enthusiasts will love wandering through the haunting walls of Alcatraz Island, while culture vultures can revel in the vast collections within the San Francisco Museum of Modern Art.

For a taste of the local vibe, hop on a cable car and ride through the quirky streets of Haight-Ashbury or explore the vibrant shops and eateries that make Chinatown sing with flavor. Green thumbs (and photographers) shouldn’t miss the Botanical Gardens in Golden Gate Park for a tranquil escape. Whether it’s the distinctive neighborhoods or the panoramic city views from Twin Peaks, every corner of San Francisco is ready to enchant you, especially when you roll into town with the reliable comfort of a Trailways bus.

Scenic photo of San Francisco, CAScenic photo of San Francisco, CAScenic photo of San Francisco, CA
Scenic photo of San Francisco, CA
Scenic photo of San Francisco, CA
Scenic photo of San Francisco, CA

City InformationforIslamorada, FL

If you're daydreaming about a tropical paradise without leaving the continental U.S., hop on a bus to Islamorada, FL. This charming town in the Florida Keys offers an unforgettable getaway with its endless adventure and laid-back vibe.

Dive straight into the turquoise waters that surround the town, perfect for snorkeling or fishing. Islamorada is famously dubbed the "Sportfishing Capital of the World," so angling enthusiasts, bring your A-game and reel in a big one! If you’re looking for more adventure, paddle through the mangrove tunnels or go kayaking at the Indian Key Historic State Park.

On land, discover the unique local flavor at family-run seafood shacks serving up the freshest catch, often with a side of stunning ocean views. For a casual dose of local culture, enjoy live music at one of the bayside bars as the sun dips beneath the horizon.

With each corner brimming with excitement or relaxation, it’s time to let Islamorada work its magic on you. So, grab those bus tickets to Islamorada, FL, and let the beautiful Keys enchant you.

Frequently Asked Questions about the Bus Ride

Interested in bus routes from San Francisco to Islamorada? Trailways offers 1 bus departing from San Francisco to Islamorada every day. Comfort, convenience, and affordability. Buy your Islamorada bus ticket today.