View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Rochester, NY to Greenville, SC

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Greenville, SC

Greenville

Bus Station, use arrow keys or tab to explore more about this bus station

Greenville, SC 29607

Bus Station
Address
1116 Woodruff Rd 
Greenville, SC 29607
Phone Number
(800) 858-8555
More Detailsabout Greenville Bus Station

City InformationforRochester, NY

Hop on a bus to Rochester, NY, and discover a treasure trove of experiences in this lively town! Known for its cultural richness and vibrant arts scene, Rochester’s got plenty to keep you entertained and delighted. Kick off your adventure with a visit to the iconic Strong National Museum of Play, where nostalgia reigns supreme, and fun is a guarantee, no matter your age. History buffs will revel in the George Eastman Museum, celebrating the birthplace of film and photography.

Craving a dash of nature? Highland Park, home to beautiful lilacs and scenic trails, offers the perfect spot for a leisurely stroll. For something more lively, the Little Theatre showcases independent films and serves up a cozy ambiance—ideal for any cinephile. And just when you think you’re done, Rochester’s culinary scene will pull you in with local eateries serving up everything from beloved garbage plates to inventive farm-to-table dishes. With its unique blend of culture and charm, Rochester is waiting to be your next favorite getaway.

Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}

City InformationforGreenville, SC

Pack your bags and get ready to fall for Greenville, SC - a town bursting with Southern charm and surprises. Hop on a bus to Greenville, SC, and discover all this gem has to offer. Start your journey by wandering through Falls Park on the Reedy, where gentle waterfalls and lush gardens provide the perfect setting for a picnic or a peaceful stroll. If you’re an art enthusiast, the Greenville County Museum of Art awaits with a stunning collection, while the local galleries dotting the area are sure to catch your eye.

Looking for adventure with a side of nature? The Swamp Rabbit Trail offers a scenic route for biking or walking, weaving through the town's vibrant neighborhoods. Make sure to swing by the Greenville Zoo for a family-friendly outing with creatures from around the globe.

Greenville’s food scene is buzzing. From quaint cafes to upscale eateries, your taste buds are in for a treat. With its blend of culture, cuisine, and charming green spaces, Greenville, SC, is calling your name. Book that bus ticket, and let the adventure begin!

Frequently Asked Questions about the Bus Ride