View Current Travel Advisories

Trailways Bus Tickets
from Roanoke, VA to Key West, FL

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Roanoke, VA to Key West, FL

Buses from Roanoke, VA to Key West, FL travel the 885mi (1424.27km) journey, taking approximately 1d, 20h, 40m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $324.58, you can find the cheapest bus tickets for as low as $324.58.

  • Distance
    885mi (1424.27km)
  • Average trip duration
  • Average bus ticket price
    $324.58
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for Key West, FL

Key West

Bus Station, use arrow keys or tab to explore more about this bus station

Key West, FL 33040

Bus Station
Address
3439 S. Roosevelt Blvd. 
Key West, FL 33040
Phone Number
(800) 858-8555
More Detailsabout Key West Bus Station

Key West (FlixBus)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Key West, FL 33040

Curbside Stop
Address
910 Caroline Street 
Key West, FL 33040
Phone Number
(800) 858-8555
More Detailsabout Key West (FlixBus) Curbside Stop

City InformationforRoanoke, VA

Your path to exploration is an easy one with a bus to Roanoke, VA, where adventure meets charm at every turn. Nestled in the scenic Blue Ridge Mountains, this town is your gateway to the great outdoors and vibrant local culture. Whether you're hiking up McAfee Knob for epic sunrise views or strolling through the colorful exhibits at the Taubman Museum of Art, Roanoke has something to delight every traveler’s fancy.

History buffs can step back in time at the O. Winston Link Museum, filled with captivating railroad photography, while culinary enthusiasts will revel in the local food scene, showcasing flavors from Southern comfort food to innovative new dishes. Don't miss out on the town's bustling markets, where you'll find everything from handmade crafts to fresh produce.

Want to immerse yourself in the local scene? Roanoke’s friendly vibe and community-centric events will make you feel right at home. Ready for your next adventure? Hop on a Trailways bus to Roanoke and make memories that won’t just fill your camera roll, but your heart too.

City InformationforKey West, FL

Step aboard a bus to Key West, FL, where the laid-back island life meets vibrant culture and history! As you cruise along the Overseas Highway, prepare to be enchanted by this colorful town. Key West isn’t just sunshine and sandy beaches, though we’ve got plenty of that. It’s also home to literary legend Ernest Hemingway’s house, where roaming six-toed cats keep things interesting.

Feeling adventurous? A snorkeling tour through the coral reefs at Dry Tortugas National Park is a must. For a touch of history, Fort Zachary Taylor’s Civil War heritage and lush surroundings offer a unique blend of learning and leisure. When hunger strikes, dig into some conch fritters or savor more refined tastes at Duval Street’s eclectic mix of eateries.

With its lively art scene, whimsical architecture, and island sunsets that are pure magic, this town invites you to kick back and relax. Hop on a bus to Key West, FL, and let the adventures begin. Your island escapade awaits!

Frequently Asked Questions about the Bus Ride

Looking to catch a bus from Roanoke to Key West? Our buses travel from Roanoke to Key West 1 time every day. Prices start at $324.58. Schedule your bus trip to Key West today!