View Current Travel Advisories

Trailways Bus Tickets
from Portland, ME to San Diego, CA

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Portland, ME to San Diego, CA

Buses from Portland, ME to San Diego, CA travel the 2618mi (4213.25km) journey, taking approximately 4d, 1h, 38m. Usually, there are 3 buses operating per day. While the average ticket price for this journey is around $320.10, you can find the cheapest bus tickets for as low as $319.63.

  • Distance
    2618mi (4213.25km)
  • Average trip duration
  • Average bus ticket price
    $320.10
  • Trips per day
    3
  • Top Carriers
    FlixBus

Bus Station Information for San Diego, CA

San Diego

Bus Station, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Bus Station
Address
4005 Taylor Street 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego Bus Station

San Diego (La Jolla - UC San Diego)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92093

Curbside Stop
Address
UCSD Health La Jolla Station 
San Diego, CA 92093
Phone Number
(858) 800-8898
More Detailsabout San Diego (La Jolla - UC San Diego) Curbside Stop

San Diego (Old Town)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Curbside Stop
Address
2728 Congress St 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego (Old Town) Curbside Stop

San Diego (SDSU - Hardy Ave)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92115

Curbside Stop
Address
5716 Hardy Ave 
San Diego, CA 92115
Phone Number
(858) 800-8898
More Detailsabout San Diego (SDSU - Hardy Ave) Curbside Stop

City InformationforPortland, ME

Ready for a coastal escape without breaking the bank? Book your bus to Portland, ME, and dive into a charming town that blends maritime heritage with modern flair. Portland boasts a vibrant arts and culture scene, delectable dining options, and picturesque scenery. Start with a leisurely wander through the historic Old Port district, where cobblestone streets lead you to unique boutiques and craft breweries.

If you're seeking a splash of nature, the Eastern Promenade offers stunning waterfront views and trails perfect for a brisk walk or a casual bike ride. Don’t skip the Portland Museum of Art, where you’ll find an impressive collection ranging from local masterpieces to international works. For seafood lovers, the town’s renowned lobster rolls are a must-try - where fresh catches are the star on every menu.

With so much culture, cuisine, and coastline to explore, Portland awaits with its unique blend of small-town charm and lively spirit. Hop on a bus to Portland, ME, and get ready to create unforgettable memories!

City InformationforSan Diego, CA

Pack your flip-flops and hop on a bus to San Diego, CA - where sunny skies and laid-back vibes effortlessly meet. Renowned for its stunning coastline and vibrant culture, San Diego offers budget-friendly adventures and unforgettable experiences. Start your journey in Balboa Park, with its lush gardens and impressive museums, perfect for a leisurely day of exploration.

Beach lovers will find paradise with miles of golden sands at popular spots like Mission Beach or the historic charm of Coronado Beach. Surfing, anyone? Don’t miss a chance to ride the waves at La Jolla Shores. If wildlife is your jam, the San Diego Zoo is world-class and not to be missed.

Dining here is a treat, from casual fish tacos by the shore to rooftop dining with views of that famous sunset. Stroll through the hip neighborhoods of North Park and Gaslamp Quarter for local shops and unique eats. Whatever draws you here, the chill pace of life ensures there's always time for one more adventure. Get started today with a bus to San Diego, CA, and soak in everything this coastal gem offers!

Scenic photo of San Diego, CAScenic photo of San Diego, CAScenic photo of San Diego, CA
Scenic photo of San Diego, CA
Scenic photo of San Diego, CA
Scenic photo of San Diego, CA

Frequently Asked Questions about the Bus Ride

Take the bus from Portland to San Diego with ease. We have multiple options (3 per day) heading from Portland to San Diego for as little as $319.63. Purchase San Diego bus tickets now.