View Current Travel Advisories

Trailways Bus Tickets
from Myrtle Beach, SC to Frederick, MD

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Frederick, MD

Frederick

Curbside Stop, use arrow keys or tab to explore more about this bus station

Frederick, MD 21701

Curbside Stop
Address
100 S. East St. 
Frederick, MD 21701
Phone Number
(800) 858-8555
More Detailsabout Frederick Curbside Stop

City InformationforMyrtle Beach, SC

Let Myrtle Beach, SC, add a splash of adventure to your itinerary without splashing out! Whether you're a beach bum or a thrill-seeker, this coastal gem has got something for everyone. Start your day with a sunrise stroll along its sprawling sandy shores, perfect for finding those elusive, picture-perfect seashells. For thrill enthusiasts, Broadway at the Beach offers a fun-filled day of shopping, dining, and entertainment with attractions like Ripley’s Aquarium and live shows. Nature lovers can head to Myrtle Beach State Park for a relaxing hike or a picnic amid stunning ocean views. Meanwhile, golf lovers won't want to miss one of the area’s famed mini-golf courses.

Feeling hungry? Local seafood shacks serve up fresh, delectable catch-of-the-day specials that turn every meal into a coastal feast. And for those looking to experience history, the Hopsewee Plantation offers a glimpse into the past.

Planning your trip? Book a bus to Myrtle Beach and soak up all the sun-soaked memories this vibrant town has to offer. Adventure waits beyond every sand dune!

City InformationforFrederick, MD

Looking for a delightful escape that balances history, nature, and culinary delights? Your bus to Frederick, MD is ready to whisk you away to this charming town. Nestled in the heart of Maryland, Frederick offers a scenic blend of cobblestone streets and rolling landscapes. History buffs will absolutely adore the National Museum of Civil War Medicine, a unique stop that sheds light on fascinating 19th-century medical practices. Meanwhile, art lovers can rejoice at the vibrant offerings of the Delaplaine Arts Center.

Catch a breath of fresh air with a visit to the Great Frederick Fairgrounds or crisscross your way through picturesque Carroll Creek Park. Whispered among locals are tales of ghost tours, adding an element of intrigue to your visit. As the sun dips, meander through the streets sparkling with local eateries. Frederick’s spirited dining scene boasts everything from crabcakes to farm-fresh twists, promising palates a feast of flavor.

Seize the opportunity to create lasting memories. Book your bus tickets to Frederick, MD and let the adventure unfold!