View Current Travel Advisories

Trailways Bus Tickets
from Mesa, AZ to San Luis Obispo, CA

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Mesa, AZ to San Luis Obispo, CA

Buses from Mesa, AZ to San Luis Obispo, CA travel the 519mi (835.25km) journey, taking approximately 17h, 5m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $114.76, you can find the cheapest bus tickets for as low as $114.76.

  • Distance
    519mi (835.25km)
  • Average trip duration
  • Average bus ticket price
    $114.76
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for San Luis Obispo, CA

San Luis Obispo (Railroad Museum)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Luis Obispo, CA 93401

Curbside Stop
Address
1940 Santa Barbara Ave 
San Luis Obispo, CA 93401
Phone Number
(800) 858-8555
More Detailsabout San Luis Obispo (Railroad Museum) Curbside Stop

City InformationforMesa, AZ

Nestled amidst the sun-drenched beauty of the Sonoran Desert, Mesa, AZ, offers a vibrant tapestry of culture, adventure, and unique charm waiting to be unraveled. As you glide into town on a comfortable bus to Mesa, get ready to be greeted by its warm local vibe and endless possibilities for exploration.

Nature enthusiasts will relish in the scenic wonder of Usery Mountain Regional Park, perfect for an invigorating hike or a serene picnic. For a taste of local culture, wander through the Mesa Arts Center, home to exquisite galleries and live performances. Feeling the call of adventure? Try paddleboarding on the serene Salt River or take a leisurely stroll through the Desert Botanical Garden.

Mesa’s dining scene, a delicious fusion of southwestern flavors and farm-to-table freshness, will have you coming back for seconds. With local artisans creating delightful keepsakes, the town doesn’t just offer experiences, it leaves imprints. Hop on a bus to Mesa, AZ, and discover the magic this dynamic city has in store.

City InformationforSan Luis Obispo, CA

Welcome to the charm of San Luis Obispo, CA, where your next adventure awaits. Nestled along California’s stunning Central Coast, this town is known for its unbeatable blend of relaxation and energy. Start your day on a high note as you hike up Bishop Peak, offering dazzling panoramic views that are worth every climb. Or, engage in local culture at Bubblegum Alley, the quirky landmark that sticks with you – literally!

Foodies will love the farm-to-table flavors at the region’s thriving restaurants, while those in the mood for exploration can wander around the unique shops and galleries in the historic downtown area. Feel the warmth of the community as you stroll through the picturesque streets, where friendly smiles are as common as the sunny skies.

Ready to make the journey? Your bus to San Luis Obispo promises not just a destination, but a pathway to delightful discoveries and cherished memories. So, grab that ticket, hop on board, and let San Luis Obispo captivate you with its laid-back yet lively allure!

Frequently Asked Questions about the Bus Ride

Enjoy an effortless bus journey from Mesa to San Luis Obispo. Our buses travel from Mesa to San Luis Obispo 1 time every day. Prices start at $114.76. Purchase San Luis Obispo bus tickets now.