View Current Travel Advisories

Trailways Bus Tickets
from Mesa, AZ to Knoxville, TN

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Mesa, AZ to Knoxville, TN

Buses from Mesa, AZ to Knoxville, TN travel the 1593mi (2563.68km) journey, taking approximately 2d, 4h, 3m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $396.06, you can find the cheapest bus tickets for as low as $332.32.

  • Distance
    1593mi (2563.68km)
  • Average trip duration
  • Average bus ticket price
    $396.06
  • Trips per day
    2
  • Top Carriers
    Greyhound Lines

Bus Station Information for Knoxville, TN

Knoxville

Curbside Stop, use arrow keys or tab to explore more about this bus station

Knoxville, TN 37914

Curbside Stop
Address
100 Kirkwood St 
Knoxville, TN 37914
Phone Number
(800) 858-8555
More Detailsabout Knoxville Curbside Stop

City InformationforMesa, AZ

Nestled amidst the sun-drenched beauty of the Sonoran Desert, Mesa, AZ, offers a vibrant tapestry of culture, adventure, and unique charm waiting to be unraveled. As you glide into town on a comfortable bus to Mesa, get ready to be greeted by its warm local vibe and endless possibilities for exploration.

Nature enthusiasts will relish in the scenic wonder of Usery Mountain Regional Park, perfect for an invigorating hike or a serene picnic. For a taste of local culture, wander through the Mesa Arts Center, home to exquisite galleries and live performances. Feeling the call of adventure? Try paddleboarding on the serene Salt River or take a leisurely stroll through the Desert Botanical Garden.

Mesa’s dining scene, a delicious fusion of southwestern flavors and farm-to-table freshness, will have you coming back for seconds. With local artisans creating delightful keepsakes, the town doesn’t just offer experiences, it leaves imprints. Hop on a bus to Mesa, AZ, and discover the magic this dynamic city has in store.

City InformationforKnoxville, TN

Roll into Knoxville, TN on a fresh set of wheels and you're in for a symphony of Southern charm and unique attractions. Nestled in the breathtaking Tennessee River Valley, this vibrant town weaves the spirit of the Smoky Mountains with its own eclectic mix of history, culture, and entertainment. Travel back in time with a visit to the historic Market Square, where street performers and local artists add a splash of color to your day. Feel the buzz at the Knoxville Museum of Art or catch a live performance at the Tennessee Theatre, where the melodies linger long after the curtains close.

Nature enthusiasts will delight in the Urban Wilderness, offering miles of trails that wind through lush landscapes just minutes from the city center. And hey, if you’re a college sports fan, catch a Tennessee Volunteers game and join the sea of orange at Neyland Stadium. Hop on a bus to Knoxville and immerse yourself in a town where every corner tells a story worth uncovering. Whether you're exploring solo or with a crew, Knoxville's welcoming warmth and dynamic spirit make it a road trip worth taking.

Frequently Asked Questions about the Bus Ride

Make your trip from Mesa to Knoxville simple by taking the bus. There are 2 trips leaving Mesa and arriving in Knoxville about 2 days 4 hours 3 minutes later every day. Get your bus ticket to Knoxville today!