View Current Travel Advisories

Trailways Bus Tickets
from Medford, OR to Hannibal, MO

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Hannibal, MO

Hannibal

Flag Stop, use arrow keys or tab to explore more about this bus station

Hannibal, MO 63401

Flag Stop
Address
4811 McMasters Avenue 
Hannibal, MO 63401
Phone Number
(800) 858-8555
More Detailsabout Hannibal Flag Stop

City InformationforMedford, OR

Looking for a slice of adventure without the hefty price tag? Hop on a bus to Medford, OR, where the great outdoors meet whimsical charm! Nestled in the enchanting Rogue Valley, Medford is a treasure waiting to be discovered. For an unforgettable day, take a scenic stroll through the lush, vine-covered hills of local vineyards or explore the awe-inspiring formations at Crater Lake National Park. It’s not just about nature, Medford boasts a lively arts scene too. Check out the Oregon Cabaret Theatre for a delightful evening of entertainment.

For the foodies among us, Medford brings the flavor with its thriving craft beer and farm-to-table dining spots, serving up epicurean delights that won’t empty your wallet. Keep your eyes peeled for unique finds at the weekly artisan markets, where local crafts showcase the town’s distinct personality.

Whether you're an adventurer or art lover, Medford's blend of scenic beauty and hearty hospitality will have you planning your next visit before you leave. Time to book that bus ride to Medford and dive into a getaway filled with discovery and charm!

City InformationforHannibal, MO

Nestled on the banks of the mighty Mississippi, Hannibal, MO, is as charming as it is historical. Well-known as the boyhood home of Mark Twain, this delightful town takes you on a whimsical journey through American literature. Dive into the nostalgic world of the Mark Twain Boyhood Home & Museum, where the tales of Huck Finn come alive in the very spots that inspired them.

Whether you're exploring the depths of Mark Twain Cave or drifting leisurely along the river on a nostalgic riverboat cruise, you'll feel a world away from the ordinary. The town's friendly vibe extends to its quaint Main Street, where shops brim with local treasures and cafés invite lingering over a warm cup of coffee.

As you soak up the rich tapestry of stories that weave through this riverside gem, don’t forget to savor a scrumptious piece of homemade pie at a local diner, leaving you both satisfied and delighted. It’s time to secure a seat on your bus to Hannibal, where stories come to life, and every visit becomes a classic tale of adventure.