View Current Travel Advisories

Trailways Bus Tickets
from Lake City, FL to San Diego, CA

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Lake City, FL to San Diego, CA

Buses from Lake City, FL to San Diego, CA travel the 2034mi (3273.40km) journey, taking approximately 2d, 19h, 15m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $393.59, you can find the cheapest bus tickets for as low as $393.59.

  • Distance
    2034mi (3273.40km)
  • Average trip duration
  • Average bus ticket price
    $393.59
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for San Diego, CA

San Diego

Bus Station, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Bus Station
Address
4005 Taylor Street 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego Bus Station

San Diego (La Jolla - UC San Diego)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92093

Curbside Stop
Address
UCSD Health La Jolla Station 
San Diego, CA 92093
Phone Number
(858) 800-8898
More Detailsabout San Diego (La Jolla - UC San Diego) Curbside Stop

San Diego (Old Town)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Curbside Stop
Address
2728 Congress St 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego (Old Town) Curbside Stop

San Diego (SDSU - Hardy Ave)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92115

Curbside Stop
Address
5716 Hardy Ave 
San Diego, CA 92115
Phone Number
(858) 800-8898
More Detailsabout San Diego (SDSU - Hardy Ave) Curbside Stop

City InformationforLake City, FL

Grab your backpack and hop on a bus to Lake City, FL, a hidden gem that promises a blend of relaxation and adventure. This charming town, dotted with scenic lakes and rich history, is a perfect escape from the daily grind. Start your day exploring the Ichetucknee Springs State Park where crystal-clear springs invite you to dive right in or float leisurely on a tube.

For those intrigued by history, the Lake City Columbia County Historical Museum showcases fascinating artifacts in a picturesque 1870s-era house. And if you’re more of a thrill seeker, don’t miss the Osceola National Forest with its endless trails primed for hiking or biking amidst lush pine canopies.

If food is your love language, a stroll downtown will lead you to cozy, family-run diners serving up Southern comfort food that’ll fill both your heart and soul. Lake City’s friendly vibe invites you to unwind and explore, all while keeping your wallet happy. Book your bus to Lake City, FL today, and get ready for a charming slice of Floridian life!

City InformationforSan Diego, CA

Pack your flip-flops and hop on a bus to San Diego, CA - where sunny skies and laid-back vibes effortlessly meet. Renowned for its stunning coastline and vibrant culture, San Diego offers budget-friendly adventures and unforgettable experiences. Start your journey in Balboa Park, with its lush gardens and impressive museums, perfect for a leisurely day of exploration.

Beach lovers will find paradise with miles of golden sands at popular spots like Mission Beach or the historic charm of Coronado Beach. Surfing, anyone? Don’t miss a chance to ride the waves at La Jolla Shores. If wildlife is your jam, the San Diego Zoo is world-class and not to be missed.

Dining here is a treat, from casual fish tacos by the shore to rooftop dining with views of that famous sunset. Stroll through the hip neighborhoods of North Park and Gaslamp Quarter for local shops and unique eats. Whatever draws you here, the chill pace of life ensures there's always time for one more adventure. Get started today with a bus to San Diego, CA, and soak in everything this coastal gem offers!

Scenic photo of San Diego, CAScenic photo of San Diego, CAScenic photo of San Diego, CA
Scenic photo of San Diego, CA
Scenic photo of San Diego, CA
Scenic photo of San Diego, CA

Frequently Asked Questions about the Bus Ride

Interested in bus routes from Lake City to San Diego? There are 1 trip leaving Lake City and arriving in San Diego about 2 days 19 hours 15 minutes later every day. Schedule your bus trip to San Diego today!