View Current Travel Advisories

Trailways Bus Tickets
from Lake City, FL to San Antonio, TX

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Lake City, FL to San Antonio, TX

Buses from Lake City, FL to San Antonio, TX travel the 952mi (1532.09km) journey, taking approximately 23h. Usually, there are 3 buses operating per day. While the average ticket price for this journey is around $216.15, you can find the cheapest bus tickets for as low as $214.73.

  • Distance
    952mi (1532.09km)
  • Average trip duration
  • Average bus ticket price
    $216.15
  • Trips per day
    3
  • Top Carriers
    Greyhound Lines

Bus Station Information for San Antonio, TX

San Antonio (Bus Station)

Bus Station, use arrow keys or tab to explore more about this bus station

San Antonio, TX 78205

24 Hours
Bus Station
Address
500 N. Saint Mary's St. 
San Antonio, TX 78205
Phone Number
(800) 858-8555
More Detailsabout San Antonio (Bus Station) Bus Station

San Antonio (Dave & Buster's)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Antonio, TX 78201

Curbside Stop
Address
440 Crossroads Blvd. 
San Antonio, TX 78201
Phone Number
(858) 800-8898
More Detailsabout San Antonio (Dave & Buster's) Curbside Stop

San Antonio (VIA Transit)

Bus Station, use arrow keys or tab to explore more about this bus station

San Antonio, TX 78201

Bus Station
Address
151 N Crossroads Blvd 
San Antonio, TX 78201
Phone Number
(858) 800-8898
More Detailsabout San Antonio (VIA Transit) Bus Station

San Antonio (Pearl District)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Antonio, TX 78215

Curbside Stop
Address
612 Avenue A 
San Antonio, TX 78215
Phone Number
(800) 858-8555
More Detailsabout San Antonio (Pearl District) Curbside Stop

City InformationforLake City, FL

Grab your backpack and hop on a bus to Lake City, FL, a hidden gem that promises a blend of relaxation and adventure. This charming town, dotted with scenic lakes and rich history, is a perfect escape from the daily grind. Start your day exploring the Ichetucknee Springs State Park where crystal-clear springs invite you to dive right in or float leisurely on a tube.

For those intrigued by history, the Lake City Columbia County Historical Museum showcases fascinating artifacts in a picturesque 1870s-era house. And if you’re more of a thrill seeker, don’t miss the Osceola National Forest with its endless trails primed for hiking or biking amidst lush pine canopies.

If food is your love language, a stroll downtown will lead you to cozy, family-run diners serving up Southern comfort food that’ll fill both your heart and soul. Lake City’s friendly vibe invites you to unwind and explore, all while keeping your wallet happy. Book your bus to Lake City, FL today, and get ready for a charming slice of Floridian life!

City InformationforSan Antonio, TX

Get ready to soak up the charm of San Antonio, TX, where rich history and vibrant culture blend seamlessly. A bus to San Antonio brings budget-savvy travelers to a city wrapped in the warmth of Texan hospitality. Whether you're a history enthusiast or seeking something fresh, this town won’t disappoint. Start by wandering along the iconic River Walk, where lush landscapes and lively cafes line meandering paths. Don't miss the chance to revisit history at the Alamo, an emblem of perseverance and pride.

For the art lovers, the San Antonio Museum of Art offers a treasure trove of global artworks, while the historic Pearl District is the perfect spot to sip locally brewed coffee and peruse eclectic shops. Feel like something a bit more adventurous? Explore the San Antonio Missions National Historical Park and immerse yourself in timeless architecture and stories.

In San Antonio, every corner whispers a tale. So pack your curiosity and book that bus to discover this jewel of a destination where you'll leave with stories worth sharing.

Scenic photo of San Antonio, TXScenic photo of San Antonio, TXScenic photo of San Antonio, TX
Scenic photo of San Antonio, TX
Scenic photo of San Antonio, TX
Scenic photo of San Antonio, TX

Frequently Asked Questions about the Bus Ride

Planning on taking the bus from Lake City to San Antonio? We have daily departures from Lake City to San Antonio starting as low as $214.73. Comfort, convenience, and affordability. Buy your San Antonio bus ticket today.