View Current Travel Advisories

Trailways Bus Tickets
from Knoxville, TN to Chillicothe, OH

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Knoxville, TN to Chillicothe, OH

Buses from Knoxville, TN to Chillicothe, OH travel the 237mi (381.41km) journey, taking approximately 21h, 30m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $148.37, you can find the cheapest bus tickets for as low as $148.37.

  • Distance
    237mi (381.41km)
  • Average trip duration
  • Average bus ticket price
    $148.37
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for Chillicothe, OH

Chillicothe

Curbside Stop, use arrow keys or tab to explore more about this bus station

Chillicothe, OH 45601

Curbside Stop
Address
760 N Bridge St 
Chillicothe, OH 45601
Phone Number
(800) 858-8555
More Detailsabout Chillicothe Curbside Stop

City InformationforKnoxville, TN

Roll into Knoxville, TN on a fresh set of wheels and you're in for a symphony of Southern charm and unique attractions. Nestled in the breathtaking Tennessee River Valley, this vibrant town weaves the spirit of the Smoky Mountains with its own eclectic mix of history, culture, and entertainment. Travel back in time with a visit to the historic Market Square, where street performers and local artists add a splash of color to your day. Feel the buzz at the Knoxville Museum of Art or catch a live performance at the Tennessee Theatre, where the melodies linger long after the curtains close.

Nature enthusiasts will delight in the Urban Wilderness, offering miles of trails that wind through lush landscapes just minutes from the city center. And hey, if you’re a college sports fan, catch a Tennessee Volunteers game and join the sea of orange at Neyland Stadium. Hop on a bus to Knoxville and immerse yourself in a town where every corner tells a story worth uncovering. Whether you're exploring solo or with a crew, Knoxville's welcoming warmth and dynamic spirit make it a road trip worth taking.

City InformationforChillicothe, OH

Get comfy on a bus to Chillicothe, OH, where small-town charm meets intriguing history and outdoor adventure. As Ohio's first capital, this delightful destination is a treasure trove for history enthusiasts and nature lovers alike. Start your journey in the historical heart of the town with a visit to the Hopewell Culture National Historical Park. Marvel at the ancient earthworks that have puzzled and inspired for generations.

Need a little more strut in your step? Wander through the city's vibrant streets and you'll encounter unique local flavors and friendly faces. The Majestic Theatre, one of the oldest theaters in the country, hosts lively performances that add a splash of culture to your itinerary. And if you're into more serene settings, stroll the scenic trails at Great Seal State Park, where rolling hills and peaceful vistas offer a perfect escape.

With your sense of adventure ignited, grab your bus tickets to Chillicothe, OH, and experience firsthand what makes this charming spot one to remember.

Frequently Asked Questions about the Bus Ride

Make your trip from Knoxville to Chillicothe simple by taking the bus. You can take one of our 1 daily trips from Knoxville to Chillicothe for prices starting from $148.37. Get your bus ticket to Chillicothe today!