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Trailways Bus Tickets
from Key West, FL to San Diego, CA

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Overview

About buses from Key West, FL to San Diego, CA

Buses from Key West, FL to San Diego, CA travel the 2208mi (3553.42km) journey, taking approximately 3d, 6h, 8m. Usually, there are 6 buses operating per day. While the average ticket price for this journey is around $362.61, you can find the cheapest bus tickets for as low as $348.52.

  • Distance
    2208mi (3553.42km)
  • Average trip duration
  • Average bus ticket price
    $362.61
  • Trips per day
    6
  • Top Carriers
    Greyhound Lines

Bus Station Information for San Diego, CA

San Diego

Bus Station, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Bus Station
Address
4005 Taylor Street 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego Bus Station

San Diego (La Jolla - UC San Diego)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92093

Curbside Stop
Address
UCSD Health La Jolla Station 
San Diego, CA 92093
Phone Number
(858) 800-8898
More Detailsabout San Diego (La Jolla - UC San Diego) Curbside Stop

San Diego (Old Town)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92110

Curbside Stop
Address
2728 Congress St 
San Diego, CA 92110
Phone Number
(858) 800-8898
More Detailsabout San Diego (Old Town) Curbside Stop

San Diego (SDSU - Hardy Ave)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Diego, CA 92115

Curbside Stop
Address
5716 Hardy Ave 
San Diego, CA 92115
Phone Number
(858) 800-8898
More Detailsabout San Diego (SDSU - Hardy Ave) Curbside Stop

City InformationforKey West, FL

Step aboard a bus to Key West, FL, where the laid-back island life meets vibrant culture and history! As you cruise along the Overseas Highway, prepare to be enchanted by this colorful town. Key West isn’t just sunshine and sandy beaches, though we’ve got plenty of that. It’s also home to literary legend Ernest Hemingway’s house, where roaming six-toed cats keep things interesting.

Feeling adventurous? A snorkeling tour through the coral reefs at Dry Tortugas National Park is a must. For a touch of history, Fort Zachary Taylor’s Civil War heritage and lush surroundings offer a unique blend of learning and leisure. When hunger strikes, dig into some conch fritters or savor more refined tastes at Duval Street’s eclectic mix of eateries.

With its lively art scene, whimsical architecture, and island sunsets that are pure magic, this town invites you to kick back and relax. Hop on a bus to Key West, FL, and let the adventures begin. Your island escapade awaits!

City InformationforSan Diego, CA

Pack your flip-flops and hop on a bus to San Diego, CA - where sunny skies and laid-back vibes effortlessly meet. Renowned for its stunning coastline and vibrant culture, San Diego offers budget-friendly adventures and unforgettable experiences. Start your journey in Balboa Park, with its lush gardens and impressive museums, perfect for a leisurely day of exploration.

Beach lovers will find paradise with miles of golden sands at popular spots like Mission Beach or the historic charm of Coronado Beach. Surfing, anyone? Don’t miss a chance to ride the waves at La Jolla Shores. If wildlife is your jam, the San Diego Zoo is world-class and not to be missed.

Dining here is a treat, from casual fish tacos by the shore to rooftop dining with views of that famous sunset. Stroll through the hip neighborhoods of North Park and Gaslamp Quarter for local shops and unique eats. Whatever draws you here, the chill pace of life ensures there's always time for one more adventure. Get started today with a bus to San Diego, CA, and soak in everything this coastal gem offers!

Scenic photo of San Diego, CAScenic photo of San Diego, CAScenic photo of San Diego, CA
Scenic photo of San Diego, CA
Scenic photo of San Diego, CA
Scenic photo of San Diego, CA

Frequently Asked Questions about the Bus Ride

Planning on taking the bus from Key West to San Diego? Trailways offers 6 buses departing from Key West to San Diego every day. Purchase San Diego bus tickets now.