View Current Travel Advisories

Trailways Bus Tickets
from Key Largo, FL to Greenville, SC

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Key Largo, FL to Greenville, SC

Buses from Key Largo, FL to Greenville, SC travel the 682mi (1097.57km) journey, taking approximately 21h, 48m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $214.39, you can find the cheapest bus tickets for as low as $189.39.

  • Distance
    682mi (1097.57km)
  • Average trip duration
  • Average bus ticket price
    $214.39
  • Trips per day
    2
  • Top Carriers
    Greyhound Lines

Bus Station Information for Greenville, SC

Greenville

Bus Station, use arrow keys or tab to explore more about this bus station

Greenville, SC 29607

Bus Station
Address
1116 Woodruff Rd 
Greenville, SC 29607
Phone Number
(800) 858-8555
More Detailsabout Greenville Bus Station

City InformationforKey Largo, FL

Looking for a relaxing yet adventurous escape? Key Largo, FL, has your name all over it. Known as the "Dive Capital of the World," this sun-drenched gem offers everything from underwater wonders to stunning sunsets that command your attention. Start your exploration at John Pennekamp Coral Reef State Park where unforgettable snorkeling or diving opportunities await. Nature enthusiasts will find plenty to adore at Dagny Johnson Key Largo Hammock Botanical State Park, where unique flora and fauna make every hike an adventure.

For a taste of local charm, the town's laid-back bars and oceanfront seafood shacks create a vibe that's as irresistible as its key lime pie. Whether you’re into kayaking through mangroves or just chilling beachside, there's no shortage of things to see and do around here.

Why wait? Let the salty air and turquoise waters lure you in. Book your bus to Key Largo, FL, and dive into an island lifestyle without breaking a sweat or the bank. Adventure is just a bus ride away!

City InformationforGreenville, SC

Pack your bags and get ready to fall for Greenville, SC - a town bursting with Southern charm and surprises. Hop on a bus to Greenville, SC, and discover all this gem has to offer. Start your journey by wandering through Falls Park on the Reedy, where gentle waterfalls and lush gardens provide the perfect setting for a picnic or a peaceful stroll. If you’re an art enthusiast, the Greenville County Museum of Art awaits with a stunning collection, while the local galleries dotting the area are sure to catch your eye.

Looking for adventure with a side of nature? The Swamp Rabbit Trail offers a scenic route for biking or walking, weaving through the town's vibrant neighborhoods. Make sure to swing by the Greenville Zoo for a family-friendly outing with creatures from around the globe.

Greenville’s food scene is buzzing. From quaint cafes to upscale eateries, your taste buds are in for a treat. With its blend of culture, cuisine, and charming green spaces, Greenville, SC, is calling your name. Book that bus ticket, and let the adventure begin!

Frequently Asked Questions about the Bus Ride

Are you taking the bus from Key Largo to Greenville? Buses depart from Key Largo to Greenville 2 times per day. Prices start at $189.39. Comfort, convenience, and affordability. Buy your Greenville bus ticket today.