View Current Travel Advisories

Trailways Bus Tickets
from Greenville, SC to Fort Myers, FL

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Greenville, SC to Fort Myers, FL

Buses from Greenville, SC to Fort Myers, FL travel the 570mi (917.32km) journey, taking approximately 20h, 38m. Usually, there are 6 buses operating per day. While the average ticket price for this journey is around $316.51, you can find the cheapest bus tickets for as low as $213.32.

  • Distance
    570mi (917.32km)
  • Average trip duration
  • Average bus ticket price
    $316.51
  • Trips per day
    6
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for Fort Myers, FL

Fort Myers

Curbside Stop, use arrow keys or tab to explore more about this bus station

Fort Myers, FL 33901

Curbside Stop
Address
2250 Widman Way 
Fort Myers, FL 33901
Phone Number
(800) 858-8555
More Detailsabout Fort Myers Curbside Stop

Fort Myers (Edison Mall)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Fort Myers, FL 33901

Curbside Stop
Address
4125 Cleveland Ave 
Fort Myers, FL 33901
Phone Number
(858) 800-8898
More Detailsabout Fort Myers (Edison Mall) Curbside Stop

Fort Myers (McDonalds - Daniels Parkway)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Fort Myers, FL 33912

Curbside Stop
Address
13600 Indian Paint Ln 
Fort Myers, FL 33912
Phone Number
(858) 800-8898
More Detailsabout Fort Myers (McDonalds - Daniels Parkway) Curbside Stop

City InformationforGreenville, SC

Pack your bags and get ready to fall for Greenville, SC - a town bursting with Southern charm and surprises. Hop on a bus to Greenville, SC, and discover all this gem has to offer. Start your journey by wandering through Falls Park on the Reedy, where gentle waterfalls and lush gardens provide the perfect setting for a picnic or a peaceful stroll. If you’re an art enthusiast, the Greenville County Museum of Art awaits with a stunning collection, while the local galleries dotting the area are sure to catch your eye.

Looking for adventure with a side of nature? The Swamp Rabbit Trail offers a scenic route for biking or walking, weaving through the town's vibrant neighborhoods. Make sure to swing by the Greenville Zoo for a family-friendly outing with creatures from around the globe.

Greenville’s food scene is buzzing. From quaint cafes to upscale eateries, your taste buds are in for a treat. With its blend of culture, cuisine, and charming green spaces, Greenville, SC, is calling your name. Book that bus ticket, and let the adventure begin!

City InformationforFort Myers, FL

Nestled on the sunny Gulf Coast, Fort Myers, FL, charms visitors with its laid-back vibe and a seamless blend of nature and history. Hop off your bus to Fort Myers and dive into an array of activities waiting just for you. For beach lovers, the soft, sandy shores and vibrant marine life of Fort Myers Beach make it a dream destination. History enthusiasts will appreciate a peek into the past at the Edison and Ford Winter Estates, where you can explore inventive legacies nestled in lush gardens.

The town’s heart beats with local flair, wander around River District, with its mix of art galleries, eclectic shops, and lively dining spots. Nature lovers won’t want to miss the chance to kayak through Four Mile Cove Ecological Preserve, bringing you up close with Southwest Florida's unique mangrove ecosystem.

Whether you're unwinding on the beach or paddling through pristine waters, Fort Myers offers a delightful getaway. So go ahead, snag those bus tickets and discover this coastal gem for yourself!

Scenic photo of Fort Myers, FLScenic photo of Fort Myers, FLScenic photo of Fort Myers, FL
Scenic photo of Fort Myers, FL
Scenic photo of Fort Myers, FL
Scenic photo of Fort Myers, FL

Frequently Asked Questions about the Bus Ride

Make it easy to get from Greenville to Fort Myers by taking a bus. There are 6 trips leaving Greenville and arriving in Fort Myers about 20 hours 38 minutes later every day. Get to Fort Myers affordably. Buy your bus ticket online.