View Current Travel Advisories

Trailways Bus Tickets
from Gainesville, FL to San Francisco, CA

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Gainesville, FL to San Francisco, CA

Buses from Gainesville, FL to San Francisco, CA travel the 2351mi (3783.56km) journey, taking approximately 3d, 2h, 24m. Usually, there are 6 buses operating per day. While the average ticket price for this journey is around $602.27, you can find the cheapest bus tickets for as low as $547.80.

  • Distance
    2351mi (3783.56km)
  • Average trip duration
  • Average bus ticket price
    $602.27
  • Trips per day
    6
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for San Francisco, CA

San Francisco

Bus Station, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94105

Bus Station
Address
425 Mission St. 
San Francisco, CA 94105
Phone Number
(800) 858-8555
More Detailsabout San Francisco Bus Station

San Francisco (5th & Townsend)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94107

Curbside Stop
Address
409 Townsend Street 
San Francisco, CA 94107
Phone Number
(800) 858-8555
More Detailsabout San Francisco (5th & Townsend) Curbside Stop

San Francisco (Fisherman's Wharf)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94109

Curbside Stop
Address
700 Beach Street 
San Francisco, CA 94109
Phone Number
(800) 858-8555
More Detailsabout San Francisco (Fisherman's Wharf) Curbside Stop

San Francisco (Daly City BART)

Curbside Stop, use arrow keys or tab to explore more about this bus station

San Francisco, CA 94014

Curbside Stop
Address
500 John Daly Blvd 
San Francisco, CA 94014
Phone Number
(800) 858-8555
More Detailsabout San Francisco (Daly City BART) Curbside Stop

City InformationforGainesville, FL

Get ready to dive into the laid-back charm of Gainesville, FL, where Southern hospitality meets college town vibrancy. Known for its lush landscapes and lively cultural scene, there's never a dull moment in this inviting town. Start off with a stroll through the Kanapaha Botanical Gardens, where natural beauty flourishes year-round. For history buffs, don’t miss the Florida Museum of Natural History, home to an impressive collection that brings the area's past to life.

Feeling adventurous? Head to Devil's Millhopper Geological State Park for a hike that promises sweeping views and a peek into Florida’s geological wonders. And let’s be honest, no journey here is complete without exploring the quirky streets of downtown Gainesville. With its unique boutiques, cozy cafes, and dynamic music scene, there’s something to guarantee you a good time.

Thinking of your next adventure? A bus to Gainesville is your ticket to a treasure trove of experiences, each as warm and welcoming as the town itself. Discover what makes this city a must-visit. Pack your bags and let Gainesville’s unique charm sweep you off your feet!

Scenic photo of Gainesville, FLScenic photo of Gainesville, FLScenic photo of Gainesville, FL
Scenic photo of Gainesville, FL
Scenic photo of Gainesville, FL
Scenic photo of Gainesville, FL

City InformationforSan Francisco, CA

When the fog rolls into San Francisco, CA, it's like a cozy invitation to savor a town bursting with iconic charm. Take your next adventure on a bus to San Francisco, and you'll find more delights than just the Golden Gate Bridge. Begin at Fisherman’s Wharf, where street performers add a whimsical touch, and sample world-class seafood. History enthusiasts will love wandering through the haunting walls of Alcatraz Island, while culture vultures can revel in the vast collections within the San Francisco Museum of Modern Art.

For a taste of the local vibe, hop on a cable car and ride through the quirky streets of Haight-Ashbury or explore the vibrant shops and eateries that make Chinatown sing with flavor. Green thumbs (and photographers) shouldn’t miss the Botanical Gardens in Golden Gate Park for a tranquil escape. Whether it’s the distinctive neighborhoods or the panoramic city views from Twin Peaks, every corner of San Francisco is ready to enchant you, especially when you roll into town with the reliable comfort of a Trailways bus.

Scenic photo of San Francisco, CAScenic photo of San Francisco, CAScenic photo of San Francisco, CA
Scenic photo of San Francisco, CA
Scenic photo of San Francisco, CA
Scenic photo of San Francisco, CA

Frequently Asked Questions about the Bus Ride

Need information on buses from Gainesville to San Francisco? Our buses travel from Gainesville to San Francisco 6 times every day. Prices start at $547.80. Schedule your bus trip to San Francisco today!