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Trailways Bus Tickets
from Frederick, MD to Knoxville, TN

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Overview

About buses from Frederick, MD to Knoxville, TN

Buses from Frederick, MD to Knoxville, TN travel the 425mi (683.97km) journey, taking approximately 18h, 25m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $159.83, you can find the cheapest bus tickets for as low as $159.83.

  • Distance
    425mi (683.97km)
  • Average trip duration
  • Average bus ticket price
    $159.83
  • Trips per day
    1
  • Top Carriers
    Greyhound Lines

Bus Station Information for Knoxville, TN

Knoxville

Curbside Stop, use arrow keys or tab to explore more about this bus station

Knoxville, TN 37914

Curbside Stop
Address
100 Kirkwood St 
Knoxville, TN 37914
Phone Number
(800) 858-8555
More Detailsabout Knoxville Curbside Stop

City InformationforFrederick, MD

Looking for a delightful escape that balances history, nature, and culinary delights? Your bus to Frederick, MD is ready to whisk you away to this charming town. Nestled in the heart of Maryland, Frederick offers a scenic blend of cobblestone streets and rolling landscapes. History buffs will absolutely adore the National Museum of Civil War Medicine, a unique stop that sheds light on fascinating 19th-century medical practices. Meanwhile, art lovers can rejoice at the vibrant offerings of the Delaplaine Arts Center.

Catch a breath of fresh air with a visit to the Great Frederick Fairgrounds or crisscross your way through picturesque Carroll Creek Park. Whispered among locals are tales of ghost tours, adding an element of intrigue to your visit. As the sun dips, meander through the streets sparkling with local eateries. Frederick’s spirited dining scene boasts everything from crabcakes to farm-fresh twists, promising palates a feast of flavor.

Seize the opportunity to create lasting memories. Book your bus tickets to Frederick, MD and let the adventure unfold!

City InformationforKnoxville, TN

Roll into Knoxville, TN on a fresh set of wheels and you're in for a symphony of Southern charm and unique attractions. Nestled in the breathtaking Tennessee River Valley, this vibrant town weaves the spirit of the Smoky Mountains with its own eclectic mix of history, culture, and entertainment. Travel back in time with a visit to the historic Market Square, where street performers and local artists add a splash of color to your day. Feel the buzz at the Knoxville Museum of Art or catch a live performance at the Tennessee Theatre, where the melodies linger long after the curtains close.

Nature enthusiasts will delight in the Urban Wilderness, offering miles of trails that wind through lush landscapes just minutes from the city center. And hey, if you’re a college sports fan, catch a Tennessee Volunteers game and join the sea of orange at Neyland Stadium. Hop on a bus to Knoxville and immerse yourself in a town where every corner tells a story worth uncovering. Whether you're exploring solo or with a crew, Knoxville's welcoming warmth and dynamic spirit make it a road trip worth taking.

Frequently Asked Questions about the Bus Ride

Looking to catch a bus from Frederick to Knoxville? Trailways has 1 Knoxville-Frederick trips starting at $159.83. Check our website for our bus tickets to Knoxville.