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Trailways Bus Tickets
from Fort Myers, FL to Knoxville, TN

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Overview

About buses from Fort Myers, FL to Knoxville, TN

Buses from Fort Myers, FL to Knoxville, TN travel the 661mi (1063.77km) journey, taking approximately 1d, 2h, 55m. Usually, there is 1 bus operating per day. While the average ticket price for this journey is around $340.80, you can find the cheapest bus tickets for as low as $340.80.

  • Distance
    661mi (1063.77km)
  • Average trip duration
  • Average bus ticket price
    $340.80
  • Trips per day
    1
  • Top Carriers
    FlixBus

Bus Station Information for Knoxville, TN

Knoxville

Curbside Stop, use arrow keys or tab to explore more about this bus station

Knoxville, TN 37914

Curbside Stop
Address
100 Kirkwood St 
Knoxville, TN 37914
Phone Number
(800) 858-8555
More Detailsabout Knoxville Curbside Stop

City InformationforFort Myers, FL

Nestled on the sunny Gulf Coast, Fort Myers, FL, charms visitors with its laid-back vibe and a seamless blend of nature and history. Hop off your bus to Fort Myers and dive into an array of activities waiting just for you. For beach lovers, the soft, sandy shores and vibrant marine life of Fort Myers Beach make it a dream destination. History enthusiasts will appreciate a peek into the past at the Edison and Ford Winter Estates, where you can explore inventive legacies nestled in lush gardens.

The town’s heart beats with local flair, wander around River District, with its mix of art galleries, eclectic shops, and lively dining spots. Nature lovers won’t want to miss the chance to kayak through Four Mile Cove Ecological Preserve, bringing you up close with Southwest Florida's unique mangrove ecosystem.

Whether you're unwinding on the beach or paddling through pristine waters, Fort Myers offers a delightful getaway. So go ahead, snag those bus tickets and discover this coastal gem for yourself!

Scenic photo of Fort Myers, FLScenic photo of Fort Myers, FLScenic photo of Fort Myers, FL
Scenic photo of Fort Myers, FL
Scenic photo of Fort Myers, FL
Scenic photo of Fort Myers, FL

City InformationforKnoxville, TN

Roll into Knoxville, TN on a fresh set of wheels and you're in for a symphony of Southern charm and unique attractions. Nestled in the breathtaking Tennessee River Valley, this vibrant town weaves the spirit of the Smoky Mountains with its own eclectic mix of history, culture, and entertainment. Travel back in time with a visit to the historic Market Square, where street performers and local artists add a splash of color to your day. Feel the buzz at the Knoxville Museum of Art or catch a live performance at the Tennessee Theatre, where the melodies linger long after the curtains close.

Nature enthusiasts will delight in the Urban Wilderness, offering miles of trails that wind through lush landscapes just minutes from the city center. And hey, if you’re a college sports fan, catch a Tennessee Volunteers game and join the sea of orange at Neyland Stadium. Hop on a bus to Knoxville and immerse yourself in a town where every corner tells a story worth uncovering. Whether you're exploring solo or with a crew, Knoxville's welcoming warmth and dynamic spirit make it a road trip worth taking.

Frequently Asked Questions about the Bus Ride

Take the bus from Fort Myers to Knoxville with ease. Book a trip to Knoxville from Fort Myers for as low as $340.80. We have 1 trip departing daily. Book bus tickets to Knoxville now.