View Current Travel Advisories

Trailways Bus Tickets
from Des Moines, IA to Buffalo, WY

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Des Moines, IA to Buffalo, WY

Buses from Des Moines, IA to Buffalo, WY travel the 892mi (1435.53km) journey, taking approximately 1d, 48m. Usually, there are 3 buses operating per day. While the average ticket price for this journey is around $267.60, you can find the cheapest bus tickets for as low as $259.15.

  • Distance
    892mi (1435.53km)
  • Average trip duration
  • Average bus ticket price
    $267.60
  • Trips per day
    3
  • Top Carriers
    Jefferson Lines

Bus Station Information for Buffalo, WY

Buffalo (Holiday Inn)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Buffalo, WY 82834

24 Hours
Curbside Stop
Address
100 Flatiron Dr. 
Buffalo, WY 82834
Phone Number
(858) 800-8898/(800) 858-8555
More Detailsabout Buffalo (Holiday Inn) Curbside Stop

City InformationforDes Moines, IA

All aboard for adventure in Des Moines, IA—a hidden gem in the heart of the Midwest that's sure to surprise and delight. Stepping off your bus to Des Moines, you'll find a town bustling with charm and brimming with activities. Start your exploration at the striking Pappajohn Sculpture Park, where art meets open air. Hungry? The lively East Village offers diverse dining that won't disappoint.

History buffs will enjoy a trip to the State Capitol, a masterpiece of 19th-century architecture with a golden dome that proudly shines over the city. Ready for some fun? Head to Adventureland Park, where thrilling rides await, or unwind in the serene beauty of the Greater Des Moines Botanical Garden.

Des Moines is also famous for its vibrant arts scene, with the Des Moines Art Center leading the charge. And don't forget the Saturday morning Downtown Farmers' Market, splendid any day of the week. Whether it’s art, architecture, or amusement parks, Des Moines serves up a hearty slice of Midwestern hospitality.

Scenic photo of Des Moines, IAScenic photo of Des Moines, IAScenic photo of Des Moines, IA
Scenic photo of Des Moines, IA
Scenic photo of Des Moines, IA
Scenic photo of Des Moines, IA

City InformationforBuffalo, WY

Looking for a destination that blends outdoor excitement with warm Western hospitality? Hop on a bus to Buffalo, WY, and find yourself surrounded by the breathtaking landscapes of the Bighorn Mountains. This town is an ideal base for adventure-seekers, offering hiking, fishing, and horseback riding as close as your doorstep. History buffs can dive into the Wild West past at the Jim Gatchell Memorial Museum, where local lore comes to life.

Buffalo takes pride in its small-business vibe, offering unique shopping and dining experiences. Visit downtown for unique local shops or grab a bite at one of the homegrown eateries serving everything from hearty steaks to fresh, local flavors. And let's not forget the Clear Creek Trail running right through town - perfect for a casual walk or bike ride.

When the day is done, catch live music at the historic Occidental Hotel, so you can say you hung out where both Hemingway and Butch Cassidy hung their hats. Ready to explore a true Wyoming gem? Buffalo is waiting to show you its friendly, laid-back spirit.

Frequently Asked Questions about the Bus Ride

Experience a smooth bus ride from Des Moines to Buffalo. We have 3 trips starting at $259.15 with an average travel time of 1 day 48 minutes. Schedule your bus trip to Buffalo today!