View Current Travel Advisories

Trailways Bus Tickets
from Clewiston, FL to Clarksdale, MS

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Clarksdale, MS

Clarksdale (Greyhound Station)

Bus Station, use arrow keys or tab to explore more about this bus station

Clarksdale, MS 38614

Bus Station
Address
1604 N State St 
Clarksdale, MS 38614
Phone Number
(800) 231-2222
More Detailsabout Clarksdale (Greyhound Station) Bus Station

City InformationforClewiston, FL

Ever thought about stepping into the heart of Florida’s countryside charm? Your bus to Clewiston, FL, is your ticket to a sweet slice of small-town wonder. Known as “America’s Sweetest Town,” Clewiston sits right beside the sprawling beauty of Lake Okeechobee, making it a perfect spot for anglers and nature lovers hoping to reel in a catch or two.

Start your journey with a walk along the scenic Lake Okeechobee Scenic Trail, ideal for kindling a spontaneous friendship with the great outdoors. For history buffs, the Clewiston Museum offers a peek into the town's past, showcasing its deep roots in sugarcane farming, a theme you'll find wrapped into the local culture.

Feeling peckish? Dive into fresh seafood or regional delights at one of Clewiston’s cozy eateries. If you’re here for a taste of local vibes, the annual Sugar Festival creates a bustling atmosphere you won’t soon forget.

Whether it’s time to unwind or explore, hopping on a bus to Clewiston delivers an experience that’s as sweet as it is memorable. Pack your curiosity, Clewiston’s ready to charm your socks off!

City InformationforClarksdale, MS

Get ready for a journey to Clarksdale, MS, a town overflowing with soulful blues and cultural heartbeats. Known as the “Home of the Blues,” Clarksdale welcomes you with music echoing from street corners to iconic juke joints like Ground Zero Blues Club and Red’s Lounge, where the rhythm gets into your bones. But the city's pulse doesn’t stop here—it flows through the Delta Blues Museum, narrating stories of legends like Muddy Waters.

When you're not tapping your feet to a soulful tune, immerse yourself in local art at Quapaw Canoe Company or explore quirky finds at eclectic shops downtown. Stroll down the historic blues trail, which doubles as a journey through time and music. Wrap up your visit with authentic Southern cuisine that’ll make you think you’ve found the ultimate comfort food haven.

Let the town’s Blues tradition be your soundtrack. Book your bus to Clarksdale now and dive into a vibrant world where music and hospitality create an unforgettable experience!