View Current Travel Advisories

Trailways Bus Tickets
from Chicago, IL to La Crosse, WI

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Chicago, IL to La Crosse, WI

Buses from Chicago, IL to La Crosse, WI travel the 782mi (1258.50km) journey, taking approximately 17h, 28m. Usually, there are 4 buses operating per day. While the average ticket price for this journey is around $252.11, you can find the cheapest bus tickets for as low as $222.54.

  • Distance
    782mi (1258.50km)
  • Average trip duration
  • Average bus ticket price
    $252.11
  • Trips per day
    4
  • Top Carriers
    Jefferson Lines

Bus Station Information for La Crosse, WI

La Crosse (Grand River Station)

Bus Station, use arrow keys or tab to explore more about this bus station

La Crosse, WI 54601

Bus Station
Address
314 Jay Street 
La Crosse, WI 54601
Phone Number
(612) 849-2658/(800) 858-8555
More Detailsabout La Crosse (Grand River Station) Bus Station

La Crosse (University of Wisconsin)

Curbside Stop, use arrow keys or tab to explore more about this bus station

La Crosse, WI 54601

Curbside Stop
Address
521 East Avenue North 
La Crosse, WI 54601
Phone Number
(858) 800-8898/(800) 858-8555
More Detailsabout La Crosse (University of Wisconsin) Curbside Stop

La Crosse (Amtrak Train Station)

Bus Station, use arrow keys or tab to explore more about this bus station

La Crosse, WI 54601

Bus Station
Address
601 St. Andrew St. 
La Crosse, WI 54601
Phone Number
(858) 800-8898
More Detailsabout La Crosse (Amtrak Train Station) Bus Station

City InformationforChicago, IL

There’s so much to see in the Windy City, you’ll be booking your next bus to Chicago before your trip is over. No matter the season, there’s plenty to do, from lounging on lakeside beaches in the summer to ice skating in Millennium Park.

Chicago’s famous for its dogs and its deep dish, if you’re looking for eats. Museums dot the map, including The Art Institute of Chicago, Field Museum, and Griffin Museum of Science and Industry. Catch a game if your sport’s in season – Bulls or Bears, Cubs or White Sox.

If you ask a local – which we always do – an Architecture Tour is on the don’t miss list. And if you’re on a budget, just go for a stroll on the Riverwalk, Navy Pier, or by “the bean” - Millennium Park’s famed Cloud Gate sculpture.

Whatever mood strikes you, Chi-town's got something to keep you busy.

Scenic photo of Chicago, ILScenic photo of Chicago, ILScenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL

City InformationforLa Crosse, WI

Set your sights on La Crosse, WI, where scenic beauty and vibrant culture welcome every traveler. Nestled along the Mississippi River, this charming town offers a refreshing blend of outdoor adventures and unique local experiences.

Whether you’re wandering through Riverside Park, gazing at the mighty river, or hiking the picturesque bluffs, La Crosse’s natural allure will instantly captivate you. History buffs should explore the Hixon House, a Victorian mansion rich with stories, while art enthusiasts can browse the Pump House Regional Arts Center, showcasing exciting exhibits.

Foodies, get ready to delight your taste buds. Dive into the local dining scene, where farm-to-table eateries and craft breweries offer savory bites and refreshing beers that reflect the town’s creative spirit. And if you’re in town during Oktoberfest, join in the festive fun with live music and Bavarian traditions.

Ready for a memorable getaway? Grab your tickets for a bus to La Crosse, and discover the delightful mix of charm and character waiting for you in this Wisconsin gem!

Frequently Asked Questions about the Bus Ride

Make your trip from Chicago to La Crosse simple by taking the bus. There are 4 trips leaving Chicago and arriving in La Crosse about 17 hours 28 minutes later every day. Book bus tickets to La Crosse now.