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Trailways Bus Tickets
from Chicago, IL to Greenville, SC

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Overview

About buses from Chicago, IL to Greenville, SC

Buses from Chicago, IL to Greenville, SC travel the 574mi (923.76km) journey, taking approximately 20h, 32m. Usually, there are 6 buses operating per day. While the average ticket price for this journey is around $211.00, you can find the cheapest bus tickets for as low as $188.

  • Distance
    574mi (923.76km)
  • Average trip duration
  • Average bus ticket price
    $211.00
  • Trips per day
    6
  • Top Carriers
    FlixBus, Greyhound Lines

Bus Station Information for Greenville, SC

Greenville

Bus Station, use arrow keys or tab to explore more about this bus station

Greenville, SC 29607

Bus Station
Address
1116 Woodruff Rd 
Greenville, SC 29607
Phone Number
(800) 858-8555
More Detailsabout Greenville Bus Station

City InformationforChicago, IL

There’s so much to see in the Windy City, you’ll be booking your next bus to Chicago before your trip is over. No matter the season, there’s plenty to do, from lounging on lakeside beaches in the summer to ice skating in Millennium Park.

Chicago’s famous for its dogs and its deep dish, if you’re looking for eats. Museums dot the map, including The Art Institute of Chicago, Field Museum, and Griffin Museum of Science and Industry. Catch a game if your sport’s in season – Bulls or Bears, Cubs or White Sox.

If you ask a local – which we always do – an Architecture Tour is on the don’t miss list. And if you’re on a budget, just go for a stroll on the Riverwalk, Navy Pier, or by “the bean” - Millennium Park’s famed Cloud Gate sculpture.

Whatever mood strikes you, Chi-town's got something to keep you busy.

Scenic photo of Chicago, ILScenic photo of Chicago, ILScenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL

City InformationforGreenville, SC

Pack your bags and get ready to fall for Greenville, SC - a town bursting with Southern charm and surprises. Hop on a bus to Greenville, SC, and discover all this gem has to offer. Start your journey by wandering through Falls Park on the Reedy, where gentle waterfalls and lush gardens provide the perfect setting for a picnic or a peaceful stroll. If you’re an art enthusiast, the Greenville County Museum of Art awaits with a stunning collection, while the local galleries dotting the area are sure to catch your eye.

Looking for adventure with a side of nature? The Swamp Rabbit Trail offers a scenic route for biking or walking, weaving through the town's vibrant neighborhoods. Make sure to swing by the Greenville Zoo for a family-friendly outing with creatures from around the globe.

Greenville’s food scene is buzzing. From quaint cafes to upscale eateries, your taste buds are in for a treat. With its blend of culture, cuisine, and charming green spaces, Greenville, SC, is calling your name. Book that bus ticket, and let the adventure begin!

Frequently Asked Questions about the Bus Ride

Take the bus from Chicago to Greenville with ease. We have multiple options (6 per day) heading from Chicago to Greenville for as little as $188.00. Book bus tickets to Greenville now.

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