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Trailways Bus Tickets
from Chicago, IL to Florence, SC

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Overview

About buses from Chicago, IL to Florence, SC

Buses from Chicago, IL to Florence, SC travel the 689mi (1108.84km) journey, taking approximately 1d, 4h, 48m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $250.67, you can find the cheapest bus tickets for as low as $236.58.

  • Distance
    689mi (1108.84km)
  • Average trip duration
  • Average bus ticket price
    $250.67
  • Trips per day
    2
  • Top Carriers
    FlixBus, Greyhound Lines

Bus Station Information for Florence, SC

Florence

Bus Station, use arrow keys or tab to explore more about this bus station

Florence, SC 29501

Bus Station
Address
611 South Irby Street 
Florence, SC 29501
Phone Number
(800) 858-8555
More Detailsabout Florence Bus Station

Florence (TA Travel Center)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Florence, SC 29501

24 Hours
Curbside Stop
Address
2301 W. Lucas St 
Florence, SC 29501
Phone Number
(858) 800-8898
More Detailsabout Florence (TA Travel Center) Curbside Stop

City InformationforChicago, IL

There’s so much to see in the Windy City, you’ll be booking your next bus to Chicago before your trip is over. No matter the season, there’s plenty to do, from lounging on lakeside beaches in the summer to ice skating in Millennium Park.

Chicago’s famous for its dogs and its deep dish, if you’re looking for eats. Museums dot the map, including The Art Institute of Chicago, Field Museum, and Griffin Museum of Science and Industry. Catch a game if your sport’s in season – Bulls or Bears, Cubs or White Sox.

If you ask a local – which we always do – an Architecture Tour is on the don’t miss list. And if you’re on a budget, just go for a stroll on the Riverwalk, Navy Pier, or by “the bean” - Millennium Park’s famed Cloud Gate sculpture.

Whatever mood strikes you, Chi-town's got something to keep you busy.

Scenic photo of Chicago, ILScenic photo of Chicago, ILScenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL

City InformationforFlorence, SC

All aboard for a delightful journey to Florence, SC, a charming town with Southern hospitality at its core. When your bus to Florence rolls in, get ready for a blend of culture, history, and good old-fashioned fun. Art lovers, kick off your adventure at the Florence County Museum and immerse yourself in regional history and breathtaking exhibits.

Craving outdoor activities? Hop on over to the Florence Rail Trail for a leisurely bike ride or a scenic walk amidst nature. If you fancy a bit of retail therapy, the Magnolia Mall will scratch that itch with a mix of national brands and local treasures. And speaking of local vibes, explore the downtown area with its quaint shops and lively arts scene.

Hungry after all that exploring? Florence has some delicious Southern cuisine options waiting to tantalize your taste buds. Before you hit the road, don't forget to snap a pic at the iconic Florence Veterans Park. With so much to discover, your ticket to Florence, SC, promises an adventure filled with laughs, local charm, and memories you'll cherish for years to come.

Frequently Asked Questions about the Bus Ride

Make your trip from Chicago to Florence simple by taking the bus. Trailways offers 2 buses departing from Chicago to Florence every day. Buy your Chicago to Florence bus ticket today.