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Trailways Bus Tickets
from Boston, MA to Saint Louis, MO

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Overview

About buses from Boston, MA to Saint Louis, MO

Buses from Boston, MA to Saint Louis, MO travel the 1040mi (1673.71km) journey, taking approximately 1d, 4h, 40m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $397.15, you can find the cheapest bus tickets for as low as $366.15.

  • Distance
    1040mi (1673.71km)
  • Average trip duration
  • Average bus ticket price
    $397.15
  • Trips per day
    2
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for Saint Louis, MO

Saint Louis

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Saint Louis, MO 63103

24 Hours
Bus Station
Address
430 S. 15th Street 
Saint Louis, MO 63103
Phone Number
(314) 231-4485/(800) 858-8555
More Detailsabout Saint Louis Bus Station

Saint Louis (Airport - STL)

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Saint Louis, MO 63145

24 Hours
Advance Notice Required
Flag Stop
Address
10701 Lambert Intl Blvd 
Saint Louis, MO 63145
Phone Number
(800) 858-8555
More Detailsabout Saint Louis (Airport - STL) Flag Stop

City InformationforBoston, MA

All aboard for Boston, MA, where history and modern flair coexist with infectious energy. Stepping off your bus to Boston is like walking onto a vibrant stage—every corner brims with stories to tell. For history buffs, the Freedom Trail is your chance to stroll through American history among landmarks like Paul Revere's House and the Old North Church. Sports fans, grab some Fenway Park magic with a Red Sox game — or at least a stadium tour if it’s off-season.

Ready to mix up your itinerary? Dive into your creative side at the Museum of Fine Arts or the Isabella Stewart Gardner Museum, where world-class art collections greet you with style. And food lovers, rejoice! From hearty clam chowder in cozy North End eateries to innovative cuisine in the Seaport District, your taste buds will thank you.

With its blend of old and new, Boston's charming neighborhoods and lively markets promise plenty of exploration. So grab a spot on that bus to Boston, MA, and immerse yourself in the town's unique local vibe.

Scenic photo of Boston, MAScenic photo of Boston, MAScenic photo of Boston, MA
Scenic photo of Boston, MA
Scenic photo of Boston, MA
Scenic photo of Boston, MA

City InformationforSaint Louis, MO

Welcome to Saint Louis, MO, a city that offers a diverse range of experiences bound to make every traveler feel right at home. Notably crowned by the iconic Gateway Arch, this urban gem is a perfect blend of historical charm and modern flair. Moving from sights to sound, immerse yourself in the musical legacy at the National Blues Museum or sway to a live jazz performance.

For animal lovers, the ever-popular Saint Louis Zoo offers free entry to a day filled with wonder and wildlife. Meanwhile, thrill-seekers might find the City Museum’s whimsical repurposed art exhibits both exhilarating and Instagram-worthy. And when it’s time to relax, grab a park bench in Forest Park and soak in its natural beauty.

No visit is complete without indulging in local eats – savor toasted ravioli or a gooey butter cake. Thriving with midwestern warmth and friendliness, this city promises an adventure that's both rich in culture and kind to the wallet. So why wait? Secure your seat on a bus to Saint Louis, and let the Gateway City open doors to new memories!

Scenic photo of Saint Louis, MOScenic photo of Saint Louis, MOScenic photo of Saint Louis, MO
Scenic photo of Saint Louis, MO
Scenic photo of Saint Louis, MO
Scenic photo of Saint Louis, MO

Frequently Asked Questions about the Bus Ride

Take the bus from Boston to Saint Louis with ease. You can take one of our 2 daily trips from Boston to Saint Louis for prices starting from $366.15. Comfort, convenience, and affordability. Buy your Saint Louis bus ticket today.