View Current Travel Advisories

Trailways Bus Tickets
from Anniston, AL to Clarksdale, MS

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Clarksdale, MS

Clarksdale (Greyhound Station)

Bus Station, use arrow keys or tab to explore more about this bus station

Clarksdale, MS 38614

Bus Station
Address
1604 N State St 
Clarksdale, MS 38614
Phone Number
(800) 231-2222
More Detailsabout Clarksdale (Greyhound Station) Bus Station

City InformationforAnniston, AL

Journey down to Anniston, AL, where Southern charm and vibrant history await your discovery. Nestled in the foothills of the Appalachian Mountains, this town offers an inviting mix of local culture and outdoor activities. Your first order of business? Embark on a scenic hike along the Chief Ladiga Trail, where nature lovers can soak up the breathtaking landscapes that surround the city. For those who cherish history, a visit to the Anniston Museum of Natural History offers enlightening exhibits that explore the region’s past.

Anniston is also known for its delightful arts scene. A stroll through the community’s beloved public art installations and galleries offers inspiration at every turn. Hungry yet? Enjoy the town's culinary offerings with a taste of classic Southern dishes served up in its cozy eateries. Each meal comes with a side of warm Southern hospitality, of course.

Whether it’s for the trails or the town’s rich tapestry, your adventure starts with a bus to Anniston. Ready to explore? Tickets are just a click away!

City InformationforClarksdale, MS

Get ready for a journey to Clarksdale, MS, a town overflowing with soulful blues and cultural heartbeats. Known as the “Home of the Blues,” Clarksdale welcomes you with music echoing from street corners to iconic juke joints like Ground Zero Blues Club and Red’s Lounge, where the rhythm gets into your bones. But the city's pulse doesn’t stop here—it flows through the Delta Blues Museum, narrating stories of legends like Muddy Waters.

When you're not tapping your feet to a soulful tune, immerse yourself in local art at Quapaw Canoe Company or explore quirky finds at eclectic shops downtown. Stroll down the historic blues trail, which doubles as a journey through time and music. Wrap up your visit with authentic Southern cuisine that’ll make you think you’ve found the ultimate comfort food haven.

Let the town’s Blues tradition be your soundtrack. Book your bus to Clarksdale now and dive into a vibrant world where music and hospitality create an unforgettable experience!