View Current Travel Advisories

Trailways Bus Tickets
from Amarillo, TX to Clarksdale, MS

Choose one way or round trip:
(*) indicates a required field
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Clarksdale, MS

Clarksdale (Greyhound Station)

Bus Station, use arrow keys or tab to explore more about this bus station

Clarksdale, MS 38614

Bus Station
Address
1604 N State St 
Clarksdale, MS 38614
Phone Number
(800) 231-2222
More Detailsabout Clarksdale (Greyhound Station) Bus Station

City InformationforAmarillo, TX

Start packing for Amarillo, TX, where the allure of the open road leads you straight into the heart of Texas charm. When hopping on a bus to Amarillo, expect a blend of quirky attractions and quintessential southern hospitality waiting to greet you. Cadillac Ranch, a fascinating art installation, invites you to channel your inner graffiti artist, while the American Quarter Horse Hall of Fame dives you into the rich history of these iconic creatures.

Beyond the attractions, Amarillo's local flavor will tempt your taste buds. Fill up on Texas BBQ with a side of small-town warmth at one of the intimate eateries lining the streets. Or, spend an afternoon exploring the stunning beauty of Palo Duro Canyon State Park, a short drive from the city.

The Golden Spread’s diversified arts scene and cowboy culture offer endless opportunities for discovery. Ready to embrace something new and friendly? Your adventure on the horizon awaits, so grab those bus tickets to Amarillo, TX, for an experience rooted in laid-back charm and vibrant culture.

City InformationforClarksdale, MS

Get ready for a journey to Clarksdale, MS, a town overflowing with soulful blues and cultural heartbeats. Known as the “Home of the Blues,” Clarksdale welcomes you with music echoing from street corners to iconic juke joints like Ground Zero Blues Club and Red’s Lounge, where the rhythm gets into your bones. But the city's pulse doesn’t stop here—it flows through the Delta Blues Museum, narrating stories of legends like Muddy Waters.

When you're not tapping your feet to a soulful tune, immerse yourself in local art at Quapaw Canoe Company or explore quirky finds at eclectic shops downtown. Stroll down the historic blues trail, which doubles as a journey through time and music. Wrap up your visit with authentic Southern cuisine that’ll make you think you’ve found the ultimate comfort food haven.

Let the town’s Blues tradition be your soundtrack. Book your bus to Clarksdale now and dive into a vibrant world where music and hospitality create an unforgettable experience!