View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Syracuse, NY to Chicago, IL

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Syracuse, NY to Chicago, IL

Buses from Syracuse, NY to Chicago, IL travel the 1211mi (1948.91km) journey, taking approximately 1d, 3h, 5m. Usually, there are 10 buses operating per day. While the average ticket price for this journey is around $339.62, you can find the cheapest bus tickets for as low as $283.06.

  • Distance
    1211mi (1948.91km)
  • Average bus duration
  • Average bus ticket price
    $339.62
  • Trips per day
    10
  • Top Carriers
    New York Trailways, Greyhound Lines, FlixBus, New York Trailways

Bus Station Information for Chicago, IL

Chicago (95th & Dan Ryan)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Chicago, IL 60628

Curbside Stop
Address
95th & Dan Ryan 
Chicago, IL 60628
Phone Number
(800) 858-8555
More Detailsabout Chicago (95th & Dan Ryan) Curbside Stop

Chicago (Cumberland Avenue)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Chicago, IL 60631

Curbside Stop
Address
5800 N Cumberland Ave 
Chicago, IL 60631
Phone Number
(800) 858-8555
More Detailsabout Chicago (Cumberland Avenue) Curbside Stop

Chicago (Bus Station)

Bus Station, use arrow keys or tab to explore more about this bus station

Chicago, IL 60607

24 Hours
Bus Station
Address
630 West Harrison Street 
Chicago, IL 60607
Phone Number
(319) 753-2864/(800) 858-8555
More Detailsabout Chicago (Bus Station) Bus Station

Chicago (Amtrak Union Station)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Chicago, IL 60606

Curbside Stop
Address
225 S. Canal St. 
Chicago, IL 60606
Phone Number
(800) 858-8555
More Detailsabout Chicago (Amtrak Union Station) Curbside Stop

City InformationforSyracuse, NY

Hop on a bus to Syracuse, NY, and get ready to dive into a city where history meets a vibrant cultural scene. Nestled at the heart of New York State, Syracuse offers a mix of attractions that cater to all types of travelers. Start your visit with a walk around the scenic campus of Syracuse University, home to striking architecture and a bustling student life. For art enthusiasts, the Everson Museum of Art is a must-see, featuring an impressive collection of American art.

If you’re a fan of the great outdoors, Green Lakes State Park is just a short drive away, offering stunning turquoise waters and picturesque trails for hiking. Be sure to check out the rich history of the Erie Canal Museum, where you can dive into New York's fascinating industrial past. And when hunger strikes, Armory Square awaits with its charming restaurants and unique shops. Whether you're an adventurer or a culture buff, Syracuse’s friendly local vibe and lively attractions make it a worthwhile stop on your travels.

Scenic photo of Syracuse, NYScenic photo of Syracuse, NYScenic photo of Syracuse, NY
Scenic photo of Syracuse, NY
Scenic photo of Syracuse, NY
Scenic photo of Syracuse, NY

City InformationforChicago, IL

There’s so much to see in the Windy City, you’ll be booking your next bus to Chicago before your trip is over. No matter the season, there’s plenty to do, from lounging on lakeside beaches in the summer to ice skating in Millennium Park.

Chicago’s famous for its dogs and its deep dish, if you’re looking for eats. Museums dot the map, including The Art Institute of Chicago, Field Museum, and Griffin Museum of Science and Industry. Catch a game if your sport’s in season – Bulls or Bears, Cubs or White Sox.

If you ask a local – which we always do – an Architecture Tour is on the don’t miss list. And if you’re on a budget, just go for a stroll on the Riverwalk, Navy Pier, or by “the bean” - Millennium Park’s famed Cloud Gate sculpture.

Whatever mood strikes you, Chi-town's got something to keep you busy.

Scenic photo of Chicago, ILScenic photo of Chicago, ILScenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL
Scenic photo of Chicago, IL

Frequently Asked Questions about the Bus Ride

Take the bus from Syracuse to Chicago with ease. We have daily departures from Syracuse to Chicago starting as low as $283.06. Buy your bus ticket to Chicago on our website.