View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Pittsburgh, PA to Saint Louis, MO

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Pittsburgh, PA to Saint Louis, MO

Buses from Pittsburgh, PA to Saint Louis, MO travel the 0mi (0.00km) journey, taking approximately 1d, 2h, 7m. Usually, there are 4 buses operating per day including direct routes. While the average ticket price for this journey is around $256.49, you can find the cheapest bus tickets for as low as $147.88.

  • Average bus duration
  • Average bus ticket price
    $256.49
  • Trips per day
    4
  • Direct routes
    2
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for Saint Louis, MO

Saint Louis

Bus Station, use arrow keys or tab to explore more about this bus station

Saint Louis, MO 63102

24 Hours
Bus Station
Address
430 S. 15th Street 
Saint Louis, MO 63102
Phone Number
(314) 231-4485/(800) 858-8555
More Detailsabout Saint Louis Bus Station

Saint Louis (Airport - STL)

Flag Stop, use arrow keys or tab to explore more about this bus station

Saint Louis, MO 63145

24 Hours
Advance Notice Required
Flag Stop
Address
10701 Lambert Intl Blvd 
Saint Louis, MO 63145
Phone Number
(319) 753-2864
More Detailsabout Saint Louis (Airport - STL) Flag Stop

City InformationforPittsburgh, PA

Set your sights on Pittsburgh, PA, where steel city vibes mix seamlessly with endless activities for every kind of traveler. With a quick bus to Pittsburgh, you're snapping up access to an array of attractions waiting to be explored. First stop? The view from Mount Washington, where you can gaze upon the sprawling skyline atop one of the city’s historic inclines. Sports fans will find a haven here, with a chance to enjoy a Pirates, Steelers, or Penguins game depending on the season.

Art lovers, make a beeline for the Andy Warhol Museum to immerse yourself in pop culture’s neon hues. Then, wander the funky streets of the Strip District, bustling with local vendors and diverse dining spots that’ll have your taste buds thanking you.

For a taste of the local spirit, catch a performance at Heinz Hall or savor a cup at one of the city’s cherished coffee shops. Pittsburgh’s unique blend of history, culture, and warm hospitality promises a hearty welcome to all who visit. So grab your bus to Pittsburgh, PA, and let the adventure begin.

Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}

City InformationforSaint Louis, MO

Welcome to Saint Louis, MO, a city that offers a diverse range of experiences bound to make every traveler feel right at home. Notably crowned by the iconic Gateway Arch, this urban gem is a perfect blend of historical charm and modern flair. Moving from sights to sound, immerse yourself in the musical legacy at the National Blues Museum or sway to a live jazz performance.

For animal lovers, the ever-popular Saint Louis Zoo offers free entry to a day filled with wonder and wildlife. Meanwhile, thrill-seekers might find the City Museum’s whimsical repurposed art exhibits both exhilarating and Instagram-worthy. And when it’s time to relax, grab a park bench in Forest Park and soak in its natural beauty.

No visit is complete without indulging in local eats – savor toasted ravioli or a gooey butter cake. Thriving with midwestern warmth and friendliness, this city promises an adventure that's both rich in culture and kind to the wallet. So why wait? Secure your seat on a bus to Saint Louis, and let the Gateway City open doors to new memories!

Frequently Asked Questions about the Bus Ride

Experience a smooth bus ride from Pittsburgh to Saint Louis. Trailways gives you the cheap, fast fares you need when you're traveling. Check our website for our bus tickets to Saint Louis.