View Current Travel Advisories
Trailways Home Page

Trailways Bus Tickets
from Philadelphia, PA to Knoxville, TN

(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Philadelphia, PA to Knoxville, TN

Buses from Philadelphia, PA to Knoxville, TN travel the 0mi (0.00km) journey, taking approximately 21h, 28m. Usually, there are 9 buses operating per day. While the average ticket price for this journey is around $176.03, you can find the cheapest bus tickets for as low as $175.33.

  • Average bus duration
  • Average bus ticket price
    $176.03
  • Trips per day
    9
  • Top Carriers
    Greyhound Lines, FlixBus

Bus Station Information for Knoxville, TN

Knoxville

Curbside Stop, use arrow keys or tab to explore more about this bus station

Knoxville, TN 37914

Curbside Stop
Address
100 Kirkwood St 
Knoxville, TN 37914
Phone Number
(800) 858-8555
More Detailsabout Knoxville Curbside Stop

City InformationforPhiladelphia, PA

Welcome to the City of Brotherly Love, also known as the birthplace of America and an epicenter of U.S. history. It's home to many historic sites, countless stories and cultural tales, and whether you’re a history buff, sports fan, film fanatic, or a foodie, Philly’s got something for you. So let freedom ring – from the Liberty Bell to your favorite Always Sunny spots.

If it’s your first visit, don’t skip the history: we’re talking Independence Hall, the Museum of the American Revolution, Betsy Ross House, the list goes on… And no matter how you decide to spend your day, make sure you work up an appetite before you book your bus tickets to Philadelphia. Those cheesesteak wars rage on, and you need to put on your battle gear.

Only one thing remains to be decided – with Whiz or without?

Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}

City InformationforKnoxville, TN

Roll into Knoxville, TN on a fresh set of wheels and you're in for a symphony of Southern charm and unique attractions. Nestled in the breathtaking Tennessee River Valley, this vibrant town weaves the spirit of the Smoky Mountains with its own eclectic mix of history, culture, and entertainment. Travel back in time with a visit to the historic Market Square, where street performers and local artists add a splash of color to your day. Feel the buzz at the Knoxville Museum of Art or catch a live performance at the Tennessee Theatre, where the melodies linger long after the curtains close.

Nature enthusiasts will delight in the Urban Wilderness, offering miles of trails that wind through lush landscapes just minutes from the city center. And hey, if you’re a college sports fan, catch a Tennessee Volunteers game and join the sea of orange at Neyland Stadium. Hop on a bus to Knoxville and immerse yourself in a town where every corner tells a story worth uncovering. Whether you're exploring solo or with a crew, Knoxville's welcoming warmth and dynamic spirit make it a road trip worth taking.

Frequently Asked Questions about the Bus Ride

Looking to catch a bus from Philadelphia to Knoxville? You can take one of our 9 daily trips from Philadelphia to Knoxville for prices starting from $175.33. Get your bus ticket to Knoxville now!

Discover our Most Popular Routes Nationwide