View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Myrtle Beach, SC to Indianapolis, IN

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.
Overview

About buses from Myrtle Beach, SC to Indianapolis, IN

Buses from Myrtle Beach, SC to Indianapolis, IN travel the 0mi (0.00km) journey, taking approximately 1d, 2h, 50m. Usually, there are 2 buses operating per day. While the average ticket price for this journey is around $170.04, you can find the cheapest bus tickets for as low as $145.05.

  • Average bus duration
  • Average bus ticket price
    $170.04
  • Trips per day
    2
  • Top Carriers
    Greyhound Lines

Bus Station Information for Indianapolis, IN

Indianapolis (Airport - IND)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Indianapolis, IN 46241

Curbside Stop
Address
7800 Col. H. Weir Cook Memorial Dr 
Indianapolis, IN 46241
Phone Number
(800) 858-8555
More Detailsabout Indianapolis (Airport - IND) Curbside Stop

Indianapolis

Bus Station, use arrow keys or tab to explore more about this bus station

Indianapolis, IN 46225

24 Hours
Bus Station
Address
350 South Illinois Street 
Indianapolis, IN 46225
Phone Number
(317) 972-6736/(800) 858-8555
More Detailsabout Indianapolis Bus Station

Indianapolis (Lugar Plaza)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Indianapolis, IN 46204

Curbside Stop
Address
230 E Washington St 
Indianapolis, IN 46204
Phone Number
(800) 858-8555
More Detailsabout Indianapolis (Lugar Plaza) Curbside Stop

Indianapolis (Northeast Exxon Station)

Curbside Stop, use arrow keys or tab to explore more about this bus station

Indianapolis, IN 46226

24 Hours
Curbside Stop
Address
7930 E 38th St 
Indianapolis, IN 46226
Phone Number
(800) 858-8555
More Detailsabout Indianapolis (Northeast Exxon Station) Curbside Stop

City InformationforMyrtle Beach, SC

Let Myrtle Beach, SC, add a splash of adventure to your itinerary without splashing out! Whether you're a beach bum or a thrill-seeker, this coastal gem has got something for everyone. Start your day with a sunrise stroll along its sprawling sandy shores, perfect for finding those elusive, picture-perfect seashells. For thrill enthusiasts, Broadway at the Beach offers a fun-filled day of shopping, dining, and entertainment with attractions like Ripley’s Aquarium and live shows. Nature lovers can head to Myrtle Beach State Park for a relaxing hike or a picnic amid stunning ocean views. Meanwhile, golf lovers won't want to miss one of the area’s famed mini-golf courses.

Feeling hungry? Local seafood shacks serve up fresh, delectable catch-of-the-day specials that turn every meal into a coastal feast. And for those looking to experience history, the Hopsewee Plantation offers a glimpse into the past.

Planning your trip? Book a bus to Myrtle Beach and soak up all the sun-soaked memories this vibrant town has to offer. Adventure waits beyond every sand dune!

Scenic photo of {{ name }}
Scenic photo of {{ name }}
Scenic photo of {{ name }}

City InformationforIndianapolis, IN

Get your adventure rolling on a bus to Indianapolis, IN, where the heart of the Hoosier State beats with a lively mix of culture, sports, and unexpected delights. Known as both the Racing Capital of the World and home to the legendary Indianapolis Motor Speedway, Indy offers enough revved-up excitement to keep gearheads grinning. But hey, motorsport isn’t the only game in town. Art lovers will find their muse at the Indianapolis Museum of Art, cradled in the stunning grounds of Newfields. For those with kids - or just young at heart - make a pit stop at the world’s largest children's museum.

Feeling outdoorsy? The sprawling White River State Park is your go-to for a leisurely afternoon, featuring trails, green spaces, and even a zoo. When hunger calls, refuel with local delicacies at bustling food joints scattered across this vibrant town. Whatever ignites your travel spirit, Indy’s charm and variety will have you hopping back on the bus to Indianapolis for another round of fun.

Frequently Asked Questions about the Bus Ride

Interested in bus routes from Myrtle Beach to Indianapolis? You can take one of our 2 daily trips from Myrtle Beach to Indianapolis for prices starting from $145.05. Find your bus ticket to Indianapolis now.