View Current Travel Advisories
Skip to Main Content
Trailways Home Page

Trailways Bus Tickets
from Knoxville, TN to Casper, WY

Choose one way or round trip:
(*) indicates a required field
Start typing the origin city to open location options, and then use the arrow keys to navigate to the origin city you want, then press enter to select that origin city
Start typing the destination city to open location options, and then use the arrow keys to navigate to the destination city you want, then press enter to select that destination city
Type the date in date format 2 digit month slash 2 digit day slash 4 digit year or press tab to use the date picker pop up calendar

Travel made simple with Trailways

Unbeatable Prices

One of the best inventories of bus tickets in one place - with exclusive fares you won't find elsewhere.

Proven Reliability

On-time travel services - trust our reputation for reliable bus transportation.

Comfort and Convenience

Numerous upgraded buses with large leather recliners, free wi-fi, and power outlets for each seat.

Bus Station Information for Casper, WY

Casper (Bus Depot)

Bus Station, use arrow keys or tab to explore more about this bus station

Casper, WY 82601

Bus Station
Address
601 N Center 
Casper, WY 82601
Phone Number
(307) 265-2353/(800) 858-8555
More Detailsabout Casper (Bus Depot) Bus Station

City InformationforKnoxville, TN

Roll into Knoxville, TN on a fresh set of wheels and you're in for a symphony of Southern charm and unique attractions. Nestled in the breathtaking Tennessee River Valley, this vibrant town weaves the spirit of the Smoky Mountains with its own eclectic mix of history, culture, and entertainment. Travel back in time with a visit to the historic Market Square, where street performers and local artists add a splash of color to your day. Feel the buzz at the Knoxville Museum of Art or catch a live performance at the Tennessee Theatre, where the melodies linger long after the curtains close.

Nature enthusiasts will delight in the Urban Wilderness, offering miles of trails that wind through lush landscapes just minutes from the city center. And hey, if you’re a college sports fan, catch a Tennessee Volunteers game and join the sea of orange at Neyland Stadium. Hop on a bus to Knoxville and immerse yourself in a town where every corner tells a story worth uncovering. Whether you're exploring solo or with a crew, Knoxville's welcoming warmth and dynamic spirit make it a road trip worth taking.

City InformationforCasper, WY

Looking for a destination that offers wide-open spaces and a warm Western welcome? Hop on a bus to Casper, WY, and prepare to explore a town that blends rugged outdoor beauty with genuine local charm. Nestled along the North Platte River, Casper is an outdoor enthusiast's dream, perfect for hiking, fishing, or just basking in panoramic views. We suggest making a day of it on Casper Mountain, where scenic trails and wildlife encounters await.

But the adventure doesn’t stop there. Dive into the town’s rich history at the National Historic Trails Interpretive Center, where the stories of pioneers and their journeys west come vividly to life. If art’s more your style, stroll through The Nicolaysen Art Museum, a neighborhood gem showcasing contemporary masterpieces in a laid-back setting.

When hunger calls, there’s no shortage of eateries dishing up hearty eats and local brews. Ready to immerse yourself in the West’s best-kept secret? Book your bus ticket to Casper, WY, and discover a place where every turn leads to something unexpected.

Frequently Asked Questions about the Bus Ride