
Buses from Hannibal, MO to Saint Louis, MO travel the 118mi (189.90km) journey, taking approximately 2h, 10m. Usually, there is 1 bus operating per day including direct routes. While the average ticket price for this journey is around $71.84, you can find the cheapest bus tickets for as low as $71.84.
Saint Louis, MO 63102
Saint Louis, MO 63145
Nestled on the banks of the mighty Mississippi, Hannibal, MO, is as charming as it is historical. Well-known as the boyhood home of Mark Twain, this delightful town takes you on a whimsical journey through American literature. Dive into the nostalgic world of the Mark Twain Boyhood Home & Museum, where the tales of Huck Finn come alive in the very spots that inspired them.
Whether you're exploring the depths of Mark Twain Cave or drifting leisurely along the river on a nostalgic riverboat cruise, you'll feel a world away from the ordinary. The town's friendly vibe extends to its quaint Main Street, where shops brim with local treasures and cafés invite lingering over a warm cup of coffee.
As you soak up the rich tapestry of stories that weave through this riverside gem, don’t forget to savor a scrumptious piece of homemade pie at a local diner, leaving you both satisfied and delighted. It’s time to secure a seat on your bus to Hannibal, where stories come to life, and every visit becomes a classic tale of adventure.



Welcome to Saint Louis, MO, a city that offers a diverse range of experiences bound to make every traveler feel right at home. Notably crowned by the iconic Gateway Arch, this urban gem is a perfect blend of historical charm and modern flair. Moving from sights to sound, immerse yourself in the musical legacy at the National Blues Museum or sway to a live jazz performance.
For animal lovers, the ever-popular Saint Louis Zoo offers free entry to a day filled with wonder and wildlife. Meanwhile, thrill-seekers might find the City Museum’s whimsical repurposed art exhibits both exhilarating and Instagram-worthy. And when it’s time to relax, grab a park bench in Forest Park and soak in its natural beauty.
No visit is complete without indulging in local eats – savor toasted ravioli or a gooey butter cake. Thriving with midwestern warmth and friendliness, this city promises an adventure that's both rich in culture and kind to the wallet. So why wait? Secure your seat on a bus to Saint Louis, and let the Gateway City open doors to new memories!
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